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BC1618

Cat. No. M11324

All AbMole products are for research use only, cannot be used for human consumption.

BC1618  Structure
Size Price Availability Quantity
5mg USD 95  USD95 In stock
10mg USD 150  USD150 In stock
25mg USD 300  USD300 In stock
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Quality Control & Documentation
Biological Activity

BC1618, an orally active Fbxo48 inhibitor, stimulates Ampk signaling (preventing activated pAmpkα from being degraded by fBXO48-mediated proteasome). BC1618 promotes mitochondrial division, autophagy and insulin sensitivity in the liver.

Chemical Information
Molecular Weight 415.45
Formula C24H24F3NO2
CAS Number 2222094-18-8
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuan Liu, et al. Nat Chem Biol. A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance

[2] R L Marquet, et al. J Cancer Res Clin Oncol. Modulation of tumor growth by allogeneic blood transfusion

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Keywords: BC1618 supplier, AMPK, inhibitors, activators

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