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AZD4625

Cat. No. M21080

All AbMole products are for research use only, cannot be used for human consumption.

AZD4625 Structure

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Quality Control & Documentation
Biological Activity

AZD4625 is a highly potent, selective, covalent and metabotropic inhibitor of the mutant GTPase KRASG12C. AZD4625 has high oral bioavailability. It is being developed to study advanced solid malignancies.

Chemical Information
Molecular Weight 486.90
Formula C24H21ClF2N4O3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Atanu Chakraborty, et al. Mol Cancer Ther. AZD4625 is a Potent and Selective Inhibitor of KRASG12C

[2] Jason G Kettle, et al. J Med Chem. Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRASG12C

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D3S-001 

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MK-1084 is a selective KRAS G12C inhibitor.

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  Catalog
Abmole Inhibitor Catalog




Keywords: AZD4625 supplier, Ras, inhibitors, activators

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