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AZA1

Cat. No. M27747

All AbMole products are for research use only, cannot be used for human consumption.

AZA1 Structure
Synonym:

Rac1/Cdc42-IN-1

Size Price Availability Quantity
5mg USD 280  USD280 In stock
10mg USD 440  USD440 In stock
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Quality Control & Documentation
Biological Activity

AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion.

Chemical Information
Molecular Weight 368.43
Formula C22H20N6
CAS Number 1071098-42-4
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Antony A Okumu, et al. Org Lett. Synthesis of the C1-C19 Domain of Azaspiracid-34

[2] M Pelin, et al. Toxicol Lett. Toxic equivalency factors (TEFs) after acute oral exposure of azaspiracid 1, -2 and -3 in mice

[3] Jane Kilcoyne, et al. Chem Res Toxicol. Epimers of azaspiracids: Isolation, structural elucidation, relative LC-MS response, and in vitro toxicity of 37-epi-azaspiracid-1

[4] Thierry Jauffrais, et al. Toxicon. Dissolved azaspiracids are absorbed and metabolized by blue mussels (Mytilus edulis)

[5] T Nomura, et al. Cancer Lett. In vivo diffusion chamber culture reduces the tumorigenicity of PCC4-aza1 teratocarcinoma cells

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Keywords: AZA1, Rac1/Cdc42-IN-1 supplier, Ras, inhibitors, activators

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