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Ac-VDVAD-CHO

Cat. No. M45309

All AbMole products are for research use only, cannot be used for human consumption.

Ac-VDVAD-CHO Structure

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Quality Control & Documentation
Biological Activity

Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46/15 nM).

Chemical Information
Molecular Weight 543.57
Formula C23H37N5O10
CAS Number 194022-51-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Michel C Maillard, et al. Bioorg Med Chem. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors

[2] Bin Fang, et al. J Mol Biol. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition

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  Catalog
Abmole Inhibitor Catalog




Keywords: Ac-VDVAD-CHO supplier, Caspase, inhibitors, activators

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