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Aβ/tau aggregation-IN-3

Cat. No. M42626

All AbMole products are for research use only, cannot be used for human consumption.

Aβ/tau aggregation-IN-3 Structure

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Quality Control & Documentation
Biological Activity

Aβ/tau aggregation-IN-3 is a potent amyloid protein aggregation inhibitor with an IC50 of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay.

Chemical Information
Molecular Weight 402.45
Formula C23H22N4O3
CAS Number 1210750-32-5
Form Solid
Solubility (25°C) DMSO 50 mg/mL (Need ultrasonic)
Storage 4°C, protect from light, dry, sealed
References

[1] Stefania Merighi et al. Int J Mol Sci. Microglia and Alzheimer's Disease

[2] Jessica Griffiths et al. Semin Cell Dev Biol. Synapse pathology in Alzheimer's disease

[3] Chenghuan Song et al. Transl Neurodegener. Immunotherapy for Alzheimer's disease: targeting β-amyloid and beyond

[4] Marc Aurel Busche et al. Nat Neurosci. Synergy between amyloid-β and tau in Alzheimer's disease

[5] Jaime Vaquer-Alicea et al. Annu Rev Biochem. Propagation of Protein Aggregation in Neurodegenerative Diseases

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Keywords: Aβ/tau aggregation-IN-3 supplier, Amyloid, inhibitors, activators

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