| Cat.No. | Name | Information |
|---|---|---|
| M54775 | Methyl tridecanoate | Methyl tridecanoate inhibits β-amyloid aggregation. Methyl tridecanoate weakly inhibits acetylcholinesterase (AChE). |
| M54716 | Trontinemab | Trontinemab is a bispecific human IgG1-κ antibody that targets amyloid β A4 precursor protein (APP) and transferrin receptor (TFRC).Trontinemab may be used in Alzheimer's disease-related studies. |
| M50214 | AC 187 TFA | AC 187 TFA is a potent, orally active and neuroprotective amylin receptor antagonist with an IC50 of 0.48 nM and a Ki of 0.275 nM. AC 187 TFA is more selective for amylin receptors than calcitonin and CGRP receptors. |
| M28783 | DC-Chol hydrochloride | DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. |
| M24855 | Donanemab | Donanemab (LY3002813) is a humanized IgG1κ monoclonal antibody directed at an N‐terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research. |
| M21812 | ALZ-801 | ALZ-801 is an orally active small molecule compound that is also an inhibitor of β-amyloid A4 (APP) and a precursor compound of homotaurine, which inhibits the formation of neurotoxic amyloid oligomers, and may be used in studies related to Alzheimer's disease (AD). |
| M14555 | Rutin hydrate | Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. |
| M14554 | Leucomethylene blue mesylate | Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (Ki of 0.12 μM), could be used for the study of Alzheimer's Disease. |
| M14552 | Hematoxylin | Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from the logwood tree, Haematoxylon campechianum. |
| M10194 | Amyloid β Protein 1-40 (TFA) | β-Amyloid (1-40) TFA is a major protein fragment found in brain plaques of Alzheimer's disease. |
| M9470 | Aftin-4 | Aftin-4 is an inducer of Aß-42 peptide production. |
| M9071 | Amyloid beta-peptide(25-35) | Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells. |
| M8968 | FPS-ZM1 | FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid-β binding to RAGE with a Ki of 25 nM. |
| M8560 | Anle138b | Anle138b is a fluorescent inhibitor of α-synuclein and prion-protein (PrPSc) aggregation that reduces the progression of prion and Parkinson′s disease in animal models. |
| M6952 | Methoxy-X04 | Methoxy-X04 is a fluorescent amyloid β detector; brain penetrant. |
| M5618 | Eprodisate disodium | Eprodisate Disodium is the orally available disodium salt form of Eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. |
| M5169 | Bavachinin | Bavachinin(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae;has potent anti-angiogenic activity. |
| M4443 | Spinosin | Spinosyn is a neuroprotective C-glycoside flavonoid isolated from the seeds of Zizyphus jujube. Spinosyn inhibits the production and polymerization of Aβ1-42 by activating the Nrf2/HO-1 pathway. |
| M4360 | Qingyangshengenin-B | Qingyangshengenin B C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against the toxicity of Aβ by decreasing the expression of Aβ at mRNA level. Qingyangshengenin B has antiepileptic activity. |
| M4216 | Timosaponin BII | Timosaponin BII is a steroid saponin found in the rhizomes of Anemarrhena asphodeloides. Timosaponin BII has neuronal protective, anti-inflammatory and antioxidant activities. |
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