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3-AP is a ribonucleotide reductase inhibitor. Also an iron chelator. Inhibits leukemia cell growth and acts in synergy with cisplatin (Cat. No.2251). Active in vivo.
| Molecular Weight | 195.24 |
| Formula | C7H9N5S |
| CAS Number | 143621-35-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 19.52 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Marjan Huizing, et al. Hermansky-Pudlak syndrome: Mutation update
[2] L Wecker, et al. 3-Acetylpyridine neurotoxicity in mice
[3] Karen Newell-Litwa, et al. Neuronal and non-neuronal functions of the AP-3 sorting machinery
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