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Tetrahydrouridine

Cat. No. M58427

All AbMole products are for research use only, cannot be used for human consumption.

Tetrahydrouridine Structure
Synonym:

THU; NSC-112907

Size Price Availability Quantity
1mg USD 125  USD125 In stock
5mg USD 310  USD310 In stock
10mg USD 500  USD500 In stock
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Quality Control & Documentation
Biological Activity

Tetrahydrouridine (THU) is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine.

Administration of 167 mg/kg Tetrahydrouridine (THU) followed by 1.0 mg/kg DAC results in death in one male and eight females. Animals surviving to scheduled termination are generally asymptomatic with no treatment related effects observed in body weights, food consumption, clinical chemistry and urinalysis for a treatment up to 1.0 mg/kg DAC in combination with 167 mg/kg Tetrahydrouridine in animals.

Chemical Information
Molecular Weight 248.23
Formula C9H16N2O6
CAS Number 18771-50-1
Form Solid
Solubility (25°C) DMSO
Water
methanol
Storage -20°C, protect from light, sealed
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Abmole Inhibitor Catalog




Keywords: Tetrahydrouridine, THU; NSC-112907 supplier, DNA/RNA Synthesis, inhibitors, activators

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