About 30 results found for searched term "3-AP" (0.043 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1644 | AG-014699 phosphate | PARP |
| PF-01367338, Rucaparib phosphate | ||
| AG-014699 (PF-01367338, Rucaparib) is a PARP inhibitor with a Ki of 1.4 nM. | ||
| M1781 | Adezmapimod (SB203580) | p38 MAPK |
| RWJ 64809; PB 203580; Adezmapimod | ||
| Adezmapimod (SB203580) is a P38 MAPK inhibitor with an IC50 of 0.3-0.5 μM, which is 10 times less selective than SAPK3(106T) and SAPK4(106T), and inhibits PKB phosphorylation with an IC50 of 3-5 μM. | ||
| M2733 | GSK2190915 | Lipoxygenase |
| AM-803, Fiboflapon | ||
| GSK2190915 (AM803), a potent FLAP inhibitor, prevents the synthesis of leukotrienes and 5-oxo-ETE, with IC50 of 76 nM for inhibition of LTB4 in human blood, provides treatment for asthma. | ||
| M3084 | Triapine | DNA/RNA Synthesis |
| 3-AP | ||
| Triapine is a potent ribonucleotide reductase inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. | ||
| M4089 | Ginsenoside-Ro | Calcium Channel |
| Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V; Ginsenoside-Ro | ||
| Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) has the antiplatelet effect of Ca2+ antagonist with IC50 of 155 μM. Ginsenoside Ro decreased TXA2 production and Ginsenoside Ro also slightly decreased COX-1 and TXAS activity. | ||
| M4189 | 3,6-Disinapoyl-sucrose | Others |
| 3,6-Disinapoyl-sucrose | ||
| M4972 | 3-Amino-5-mercapto-1,2,4-triazole | Plant growth regulators |
| Amitrole (3-amino-1,2,4-triazole) is a widely used herbicide. | ||
| M5297 | Q203 | Anti-infection |
| Q-203; Q 203; IAP6 | ||
| Q203 (IAP6) is a midazopyridine amide compound. Q203 is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium. IC50 & Target: MIC50: 2.7 nM (Mycobacterium tuberculosis H37Rv). | ||
| M5624 | Eslicarbazepine Acetate | BACE |
| BIA 2093, Zebinix, Exalief, Stedesa, Aptiom | ||
| Eslicarbazepine acetate is an antiepileptic drug. | ||
| M6332 | 3-AP | DNA/RNA Synthesis |
| 3-AP; PAN-811; OCX191; NSC663249 | ||
| 3-AP is a ribonucleotide reductase inhibitor; also an iron chelator. | ||
| M8426 | 3-AP-Me | Others |
| 3-AP-Me is a dimethyl derivative of the ribonucleotide reductase inhibitor 3-AP (SML0568). | ||
| M10202 | 1-Thioglycerol | Others |
| 3-Mercapto-1,2-propanediol | ||
| 1-Thioglycerol, a derivatization reagent, is used to study the pH-sensitive photoluminescence of aqueous thiol-capped CdTe nanocrystals. | ||
| M10210 | Amylin, amide, human | Peptides |
| Amylin (1-37) human amide; DAP amide human | ||
| Amylin, amide, human is a 37-amino acid polypeptide, it is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. | ||
| M10222 | COG 133 | Peptides |
| COG133; apoE(133-149) | ||
| COG 133 is a fragment of Apolipoprotein E (APOE) peptide with potent anti-inflammatory and neuroprotective effects. | ||
| M11506 | Ovalbumin (323-339) (chicken, japanese quail) | Peptides |
| OVA (323-339);OVA Peptide 323-339 | ||
| OVA Peptide (323-339) is an MHC Class II (H-2B) restricted OVA Peptide epitope that binds to the L-A (D) region of Class II MHC protein. It is widely used to study the natural properties of Class II MHC peptide binding and the mechanism of T cell activation. It is also commonly used to study immune allergic reactions, including asthma and food allergies. | ||
| M15042 | Recombinant Human Adiponectin (CHO) | Recombinant Proteins |
| Acrp-30; GBP-28; Apm-1 | ||
| Adiponectin is an important adipocytokine involved in the control of fat metabolism and insulin sensitivity. It is made only by fat cells and secreted into plasma. Protein structure: Acrp30 (GLU19-ASN244), Accession # : Q15848. | ||
| M15043 | Recombinant Human Adiponectin/Acrp30 (HEK 293) | Recombinant Proteins |
| Acrp-30; GBP-28; Apm-1 | ||
| Adiponectin is an important adipocytokine involved in the control of fat metabolism and insulin sensitivity. It is made only by fat cells and secreted into plasma. Protein structure: Acrp30 (Lys101-ASN244), Accession # ：Q15848. | ||
| M14177 | p38-α MAPK-IN-1 | p38 MAPK |
| p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. | ||
| M14178 | p38 MAPK-IN-1 | p38 MAPK |
| p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability. | ||
| M14639 | 1,3,6,8-Tetrahydroxynaphthalene | Others |
| 1,3,6,8-THN; T4HN | ||
| 1,3,6,8-Tetrahydroxynaphthalene (T4HN) is an indispensable precursor to DHN (1,8-Dihydroxynaphthalene) melanin and is an unique symmetrical compound of polyketide origin. | ||
| M16523 | Ailanthone | Androgen Receptor |
| Δ13-Dehydrochaparrinone | ||
| Ailanthone is a potent inhibitor of both full-length androgen receptor (AR) (IC50=69 nM) and constitutively active truncated AR splice variants (AR1-651 IC50=309 nM). | ||
| M16650 | 3,6-Dimethoxyapigenin | Flavonoids |
| 3,6-Dimethoxyapigenin | ||
| M16655 | 8,3'-Diprenylapigenin | Flavonoids |
| 8,3'-Diprenylapigenin | ||
| M16689 | 3,8''-Biapigenin | Flavonoids |
| 3,8''-Biapigenin | ||
| M17049 | Methyl 1,4-bisglucosyloxy-3-prenyl-2-naphthoate | Phenols |
| Methyl 1,4-bisglucosyloxy-3-prenyl-2-naphthoate | ||
| M17431 | 3-Hydroxychimaphilin | Quinones |
| 3-Hydroxychimaphilin | ||
| M17451 | 3,6'-Disinapoylsucrose | Saccharides |
| 3,6'-Disinapoylsucrose | ||
| M17938 | Bacoside A, mixture of Bacoside A3, Bacopaside II, Bacopaside X and Bacopasaponin C | Others |
| Bacoside A, mixture of Bacoside A3, Bacopaside II, Bacopaside X and Bacopasaponin C | ||
| M17948 | 1,4-dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside | Others |
| 1,4-dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside | ||
| M18040 | 2-Amino-3-carboxy-1,4-naphthoquinone | Others |
| 2-Amino-3-carboxy-1,4-naphthoquinone | ||
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