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Antipain dihydrochloride is a protease inhibitor. Antipain dihydrochloride inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride also restricts uterine DNA synthesis and function in mice.
Antipain dihydrochloride (100 μg/g body wt; i.p.; at 12h intervals from 0 to 120 h or 240 to 360 h) shows inhibitory effect on Urethane-induced lung neoplasia in mice.
| Molecular Weight | 677.62 |
| Formula | C27H46Cl2N10O6 |
| CAS Number | 37682-72-7 |
| Solubility (25°C) | Water 50 mg/mL |
| Storage | -20°C, sealed |
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