|M9738||LX2761||LX2761 is a locally acting SGLT1 and SGLT2 inhibitor in vitro with IC50 values of 2.2 nM and 2.7 nM for hSGLT1 and hSGLT2, respectively.|
|M8956||Canagliflozin hemihydrate||Canagliflozin hemihydrate (JNJ-28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM.|
|M5551||Dapagliflozin ((2S)-1,2-propanediol, hydrate)||Dapagliflozin(BMS512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) is in development for the treatment of type 2 diabetes mellitus (T2DM).|
|M5249||LX-4211||LX-4211 is an oral dual SGLT1/SGLT2 inhibitor with IC50 of 36 nM and 1.8 nM, respectively.|
|M4607||Phloretin||Phloretin is a dihydrochalcone found in apple tree leaves, which shows beneficial effects on diabetes.|
|M4606||Phloridzin||Phloridzin is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively.|
|M2667||Empagliflozin||Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6.|
|M2002||Canagliflozin||Canagliflozin is a potent, selective sodium glucose co-transporter 2 inhibitor.|
|M1937||Dapagliflozin||Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2).|
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