| Cat.No. | Name | Information |
|---|---|---|
| M19285 | Vitamin A | Vitamin A (Retinol) is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs. |
| M2241 | Adapalene | Adapalene is a third-generation topical retinoid, it is a potent RAR agonist, with AC50 values of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene is also an MST1 agonist. |
| M7568 | AM580 | AM580 is a selective RARα agonist with IC50 and EC50 of 8 nM and 0.36 nM, respectively. |
| M56782 | Fluorobexarotene | Fluorobexarotene is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. |
| M43837 | KCL-286 | KCL-286 is an orally active retinoic acid receptor-beta (RAR-beta) agonist for studies related to spinal cord injury. |
| M42602 | XS-060 | XS-060 is a potent anticancer agent and RXRα antagonist. |
| M42601 | BPA-B9 | BPA-B9 is a RXRα ligand and antagonist targeting the pRXRα-PLK1 interaction. |
| M42600 | ER 50891 quarterhydrate | ER 50891 quarterhydrate is a potent antagonist of retinoic acid receptor α(RARα). |
| M42599 | 4-Hydroxyretinoic acid | 4-Hydroxyretinoic acid (4-HRA) is a naturally occurring retinoid derivative with diverse biological effects. |
| M42598 | K-80001 | K-80001 is an RXRα-binder and COX-1/2 inhibitor, with IC50s of with an IC50 of 82.9μM, 3.4μM, 1.2μM for RXRα, COX-1 and COX-2, respectively. |
| M42597 | HX630 | HX630 is a potent retinoic acid X receptor (RXR) agonist, can induce apoptosis, has anti-tumor effect, and can be used in Cushing's disease research. |
| M21366 | AGN194204 | AGN194204 (IRX4204) is inactive against RAR and is an orally active and selective RXR agonist with Kd values of 0.4 nM, 3.6 nM and 3.8 nM for RXRα, RXRβ and RXRγ, respectively, and EC50s of 0.2 nM, 0.8 nM and 0.08 nM. AGN194204 has anti-inflammatory and anti-cancer effects. |
| M18161 | 16α-Hydroxytrametenolic acid | 16α-Hydroxytrametenolic acid |
| M14529 | Talarozole | Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). |
| M14524 | Tarenflurbil | Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM. |
| M11052 | Bigelovin | Bigelovin is a sesquiterpene lactone isolated from sea lilies and is an α agonist of the selective retinoid X receptor α. Bigelovin exerts antitumor activity by inducing apoptosis and autophagy. Bigelovin regulates the mTOR signal path by suppressing the generation of ROS. |
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