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AGN194204 (IRX4204) is inactive against RAR and is an orally active and selective RXR agonist with Kd values of 0.4 nM, 3.6 nM and 3.8 nM for RXRα, RXRβ and RXRγ, respectively, and EC50s of 0.2 nM, 0.8 nM and 0.08 nM. AGN194204 has anti-inflammatory and anti-cancer effects.
Molecular Weight | 352.51 |
Formula | C24H32O2 |
CAS Number | 220619-73-8 |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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