| Cat.No. | Name | Information |
|---|---|---|
| M4974 | GW4869 2HCl | GW4869 (GW69A, GW554869A) is a noncompetitive inhibitor of neutral Smase (spspingolipase) with IC50 of 1 μM. GW4869 is also an inhibitor of exosome biogenesis/release, followed by endotoxin (LPS) challenge. GW4869 could effectively inhibit the generation of exosomes in macrophages and in vivo. |
| M6074 | AA26-9 | AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. |
| M3969 | Polydatin | Polydatin (Piceid), the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum, with biological properties, such as anti-inflammation, anti-oxidative and nephroprotective effects. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses. |
| M5201 | FIPI | FIPI inhibited both PLD1 and PLD2 in a dose-dependent manner, with 50% loss of activity observed at approximately 25 nM. |
| M5170 | U73122 | U73122 is a potent inhibitor of phospholipase C, phospholipase A2 and 5-LO (5-lipoxygenase). |
| M4144 | Tanshinone-I | Tanshinone-I |
| M3969 | Polydatin | Polydatin (Piceid), the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum, with biological properties, such as anti-inflammation, anti-oxidative and nephroprotective effects. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses. |
| M2759 | Darapladib | Darapladib (SB-480848) is a selective and orally active inhibitor of Lp-PLA2 with IC50 of 0.25 nM. |
| M2638 | Difluprednate | Difluprednate (difluoroprednisolone butyrate acetate, or DFBA) is a synthetic difluorinated prednisolone derivative, it originally developed for dermatologic applications. |
| M1935 | LY315920 | LY315920 is a potent, selective inhibitor of recombinant human, group IIA, nonpancreatic secretory PLA2 (sPLA2). |
| M56776 | ML-298 | ML298 is a potent and selective inhibitor of Phospholipase D2 (PLD2) with an IC50 of 355 nM. |
| M56775 | LCL521 | LCL521 is an acid ceramidase (ACDase) inhibitor. |
| M56774 | SPK-601 | SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC). |
| M56773 | CCT129957 | CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. |
| M56772 | ONO-RS-082 | ONO-RS-082 is an inhibitor of phospholipase A (PLA). |
| M56771 | Giripladib | Giripladib (PLA-695) is a indole-based inhibitor of cytosolic phospholipase A2 (cPLA2). |
| M56770 | Pyrrophenone | Pyrrophenone is a potent and specific cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 4.2 nM. |
| M56768 | sPLA2-X Inhibitor 31 | sPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively. |
| M56767 | LCL521 dihydrochloride | LCL521 dihydrochloride is an acid ceramidase (ACDase) inhibitor. |
| M56766 | VU0155069 hydrochloride | VU0155069 hydrochloride (CAY10593 hydrochloride) is a potent selective phospholipase D (PLD) inhibitor. |
| M45028 | trans-4-phenylbut-3-en-2-one | trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). |
| M43812 | SYN-020 | SYN-020 is an orally active recombinant bovine intestinal alkaline phosphatase (IAP) for studies related to digestive disorders. |
| M43811 | IIAEK | IIAEK is a novel cholesterol-lowering pentapeptide derived from bovine milk β-lactoglobulin that targets intestinal alkaline phosphatase (IAP) and improves cholesterol metabolism through the specific activation of IAP and down-regulation of ABCA1. Sequence: Ile-Ile-Ala-Glu-Lys |
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