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VU-0155069

Cat. No. M8927

All AbMole products are for research use only, cannot be used for human consumption.

VU-0155069 Structure
Size Price Availability Quantity
5mg USD 150  USD150 In stock
10mg USD 250  USD250 In stock
25mg USD 550  USD550 In stock
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Quality Control & Documentation
Biological Activity

VU-0155069 is a potent and selective phospholipase D1 (PLD1) inhibitor with IC50 values of 46 and 933 nM for PLD1 and PLD2, respectively. VU0155069 inhibits migration of human and mouse breast cancer cell lines in transwell assays. VU0155069 significantly decreases invasive migration in breast cancer cell lines (MDA-231, 4T1 and PMT).

Chemical Information
Molecular Weight 462.97
Formula C26H27ClN4O2
CAS Number 1130067-06-9
Solubility (25°C) DMSO: ≥ 20 mg/mL
Ethanol: ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sulzmaier FJ, et al. Oncogene. PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D.

[2] Scott SA, et al. Nat Chem Biol. Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.

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  Catalog
Abmole Inhibitor Catalog




Keywords: VU-0155069 supplier, Phospholipase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



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