Inhibitors
Cat.No. | Name | Information |
---|---|---|
M9360 | Dicoumarol | Dicoumarol is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively. |
M7562 | BX517 | BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM. |
M4832 | NVP-BAG956 | NVP-BAG956 is a potent, ATP-competitive and selective dual PDK1 and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively). |
M3731 | HS-173 | HS-173 is a potent PI3Kα inhibitor with IC50 of 0.8 nM. |
M2311 | BX-912 | BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM. |
M2310 | BX-795 | BX795 is a potent and specific TBK1, IKKε and PDK-1 inhibitor with IC50 of 6 nM, 41 nM and 111 nM, respectively. |
M2115 | GSK2334470 | GSK2334470 is a highly specific and potent inhibitor of PDK1 with IC50 of 10 nM. |
M1848 | OSU-03012 | OSU-03012 is a novel and potent inhibitor of PDK-1 with an IC50 of 5 µM. |
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