PDK1 3'-phosphoinositide-dependent kinase 1

Inhibitors

Cat.No.	Name	Information
M20816	PS210	PS210 is a potent activator of PDK1 that binds to the PIF-pocket and allosterically modulates the active site of PDK1.
M20385	WAY-299338	WAY-299338 is a modulator of the Protein Kinase PDK1.
M20367	WAY-298630	WAY-298630 is a PDK1 modulator
M20162	WAY-352098	WAY-352098 is a modulator of the Protein Kinase PDK1
M9360	Dicoumarol	Dicoumarol is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively.
M7562	BX517	BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM.
M4832	NVP-BAG956	NVP-BAG956 is a potent, ATP-competitive and selective dual PDK1 and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively).
M3731	HS-173	HS-173 is a potent PI3Kα inhibitor with IC50 of 0.8 nM.
M2311	BX-912	BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM.
M2310	BX-795	BX795 is a potent and specific TBK1, IKKε and PDK-1 inhibitor with IC50 of 6 nM, 41 nM and 111 nM, respectively.
M2115	GSK2334470	GSK2334470 is a highly specific and potent inhibitor of PDK1 with IC50 of 10 nM.
M1848	OSU-03012	OSU-03012 is a novel and potent inhibitor of PDK-1 with an IC50 of 5 µM.