Free shipping on all orders over $ 500

Recently Added

Sign In
Sign Up
Contact Us

PS210

Cat. No. M20816

All AbMole products are for research use only, cannot be used for human consumption.

PS210 Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.

Quality Control & Documentation

Purity: >99%
COA
MSDS

Product Information

Biological Activity

PS210 is a potent activator of PDK1 that binds to the PIF-pocket and allosterically modulates the active site of PDK1.

Chemical Information

Molecular Weight	380.31
Formula	C19H15F3O5
CAS Number	1221962-86-2
Solubility (25°C)	DMSO 76 mg/mL
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Jun Hu, et al. Chem Sci. Different phosphorylation and farnesylation patterns tune Rnd3-14-3-3 interaction in distinct mechanisms

[2] A Paunović, et al. Porto Biomed J. Evaluation of clinical characteristics as indicators for shunt procedure in patients with medulloblastoma: PS210

[3] Wei Liu, et al. J Mol Model. Discovery of SBF1 as an allosteric inhibitor targeting the PIF-pocket of 3-phosphoinositide-dependent protein kinase-1

[4] Constanze Schelhorn, et al. Sci Rep. Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation

[5] Katrien Busschots, et al. Chem Biol. Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site

Related PDK1 Products
MP7 MP7 (PDK1 inhibitor) is a phosphoinositide-dependent kinase-1 (PDK1) inhibitor.
PDKtide PDKtide is a biological active peptide.
PDK1-IN-RS2 PDK1-IN-RS2 is a mimic of peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor with a Kd of 9 μM. PDK1-IN-RS2 suppresses the activation of the downstream kinases S6K1 by PDK1.
PS47 PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48.
WAY-299338 WAY-299338 is a modulator of the Protein Kinase PDK1.

Catalog

Abmole Inhibitor Catalog

Keywords: PS210 supplier, PDK1, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

Get to Know Us

Customer Support

Resources

Contact Us

Tel: +1-800-660-8580
Email: [email protected]

Tel: +32 (0)2 738 09 61
Email: [email protected]

Worldwide Distributors

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.