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Parasite Antiparasitics

Cat.No.  Name Information
M3209 Oxfendazole Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic.
M5841 Oxibendazole Obendazole is a class of benzimidazole compounds that interfere with metabolic pathways and are used to protect horses and some domestic pets from infections with roundworms, strongyworms, pinworms and lungworms.
M5819 Nitromide Nitromide is an anti-parasitic agent.
M5790 Milbemycin oxime Milbemycin oxime is a veterinary drug from the group of milbemycins, used as a broad spectrum antiparasitic.
M5691 Hexylresorcinol Hexylresorcinol is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.
M5606 Eflornithine hydrochloride hydrate Eflornithine (DFMO; Difluoromethylornithine) hydrochloride hydrate inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours.
M5582 Dinitolmide Dinitolmide is a fodder additive for poultry, used to prevent coccidiosis infections.
M5573 Diethylcarbamazine citrate Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements.
M5571 Diclazuril Diclazuril is an anti-coccidial drug.
M5556 DEET DEET is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects.
M5539 Crotamiton Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic. It is a prescription lotion based medicine that is applied to the whole body to get rid of the scabies parasite.
M5529 Clofentezine Clofentezine, a growth inhibitor, has sublethal effects on life-table parameters of Tetranychus urticae Koch females.
M5452 Bephenium hydroxynaphthoate Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator.
M5451 Benzyl benzoate Benzyl benzoate is an orally active anti-scabies agent, acaricide (EC50= 0.06 g/m2) and fungicide. Benzyl benzoate is an angiotensin II (Ang II) inhibitor with antihypertensive effects.
M5421 Artemotil Artemotil (β-Arteether) has antimalarial activity for the treatment of chloroquine-resistant Plasmodium falciparum malaria with an IC50 of 1.61 nM. Artemotil also has central nervous system (CNS) neurotoxicity and anorectic toxicity in rats, dogs and monkeys.
M5132 Quinacrine Dihydrochloride Dihydrate Quinacrine Hydrochloride Hydrate (Mepacrine Hydrochloride) is an antimalarial that has anti-tumor effects in vivo and in vitro. Quinacrine hydrochloride hydrate inhibits NF-κB, activates p53 signal transduction and induces apoptosis in tumor cells.
M5021 Dinotefuran Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
M4991 Dihydroartemisinin Dihydroartemisinin is a potent anti-malaria agent. Dihydroartemisinin, a derivative of artemisinin in which the C-10 lactone group is replaced by hemiacetals and active metabolites of all artemisinin compounds, is a widely used antimalarial compound that effectively induces iron death in acute myeloid leukemia cells (HL60, KG1, and THP-1) by regulating iron metabolism.
M4910 Secnidazole Secnidazole (flagellate) is a nitroimidazoles anti - infective compound.
M4892 GNF179 GNF179 is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2).
M4886 Selamectin Selamectin is an antiparasitic agent and insect repellent that activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent filariasis, lymphatic filariasis and nematode infection. Selamectin is also an effective p-glycoprotein substrate and inhibitor with IC50 of 120 nM.




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