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Acivicin

Cat. No. M8286

All AbMole products are for research use only, cannot be used for human consumption.

Acivicin Structure
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1mg USD 155  USD155 1-2 Weeks
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Quality Control & Documentation
Biological Activity

Acivicin is an antibiotic that inhibits g-glutamyl transpeptidase and transmembrane glutathione transport. Acivicin is a potent antitumor agent that induces apoptosis in human lymphoblastoid cells.

Chemical Information
Molecular Weight 178.57
Formula C5H7ClN2O3
CAS Number 42228-92-2
Form Solid
Solubility (25°C) Water: 10 mg/mL (warmed)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gatan Roy, et al. Decreased glutamate transport in acivicin resistant Leishmania tarentolae

[2] Andrew S Mendiola, et al. Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

[3] Hoffman B M Lantum, et al. Acivicin-induced alterations in renal and hepatic glutathione concentrations and in gamma-glutamyltransferase activities

[4] D S Poster, et al. Acivicin. An antitumor antibiotic

[5] R H Earhart, et al. Acivicin in 1985

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