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Parasite Antiparasitics

Cat.No.  Name Information
M3209 Oxfendazole Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic.
M22241 Eflornithine hydrochloride Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase.
M19448 Ajugol Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC50 of 31.8 μg/mL.
M19424 Musizin Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor, it stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK. Nepodin (Musizin) has antidiabetic and antimalarial activities.
M19379 Myrrhone Myrrhone is a terpenoid compound with antiplasmodial effects.
M19345 Euphorbol Euphorbadienol (alpha-Euphorbol) is a triterpenic compound, which has antileishmanial and antitrypanosomal activity. The derivatives of Euphorbadienol can be used as elicitors of disease resistance.
M19313 Pendulone Pendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 µM. Pendulone also has antileishmanial, antibacterial and anticancer activity.
M19296 Estragole Estragole (4-Allylanisole) is a major component of the essential oil of many plants. Estragole dose-dependently blocks nerve excitability. Estragole displays anti-toxoplasma activity.
M19275 Licarin A (±)-Licarin A ((±)-trans-Dehydrodiisoeugenol) is a dihydrobenzofuran neolignan, the resultant of an oxidative coupling reaction of isoeugenol and horseradish peroxidase (HRP) enzyme.
M19171 Cratoxylone Cratoxylone, isolated from the bark of Cratoxylum Cochinchinense, possesses antiplasmodial activity.
M18213 13α,21-Dihydroeurycomanone 13α,21-Dihydroeurycomanone
M18112 1,3-Dilinoleoyl-2-oleoylglycerol 1,3-Dilinoleoyl-2-oleoylglycerol
M7680 PK 11195 PK 11195 is a peripheral benzodiazepine antagonist. PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), with IC50 values of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively.




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