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Parasite Antiparasitics

Cat.No.  Name Information
M3209 Oxfendazole Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic.
M4910 Secnidazole Secnidazole (flagellate) is a nitroimidazoles anti - infective compound.
M4892 GNF179 GNF179 is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2).
M4886 Selamectin Selamectin is an antiparasitic agent and insect repellent that activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent filariasis, lymphatic filariasis and nematode infection. Selamectin is also an effective p-glycoprotein substrate and inhibitor with IC50 of 120 nM.
M4669 Tuberostemonine Tuberostemonine is an alkaloid, an antimalarial that targets plasmodium falciparum ferridogen-NADP + reductase (pfFNR).
M4645 Filixic-acid-ABA Filixic-acid-ABA
M4583 (-)-Maackiain Maackiain (DL-Maackiain) was separated from Maackia amurensis Rupr. Et Maxim. Maackiain (DL-Maackiain) is a larval insecticide against Aedes aegypti with a LD50 of 21.95 μg/ mL. Maackiain (DL-Maackiain) induces DNA fragmentation into oligonucleosome size fragments, similar to apoptotic characteristics such as HL-60 cells.
M4425 3-Butylidenephthalide 3-butylidenephthalide (i.e. 3-butylidenephthalide) is a phthalic anhydride derivative identified from Ligusticum chuanxiong Hort. It has insecticidal activity (LC50 value of 1.56 mg/g for Spodoptera Litura Spodoptera).
M4285 Harpgide Harpgide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL.
M3990 Betulonic acid Betulinic acid (Betulinic acid) is an inhibitor of eukaryotic cell topoisomerase I with IC50 value of 5 μM. It has anti-inflammatory, anti-malaria, anti-AIDS and anti-tumor activities. Betulinic acid is also a new nF-KB agonist.
M3604 Sulfadoxine Sulfadoxine is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.
M3441 Clorsulon Clorsulon is used in the treatment of Fasciola hepatica infections in calves and sheep.
M3245 Fenbendazole Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC5 of about 0.01 μg/ml
M3081 Toltrazuril Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
M3061 Tetramisole hydrochloride Tetramisole is a mixture of dextro- and levo isomers used as an anthelmintic.
M2986 Ronidazole Ronidazole is an antiprotozoal agent.
M2958 Primaquine Diphosphate Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.
M2922 Pentamidine dihydrochloride Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.
M2640 Dimetridazole Dimethyl azole is a nitroimidazole compound that is infected by antigenic animals.
M2616 Decoquinate Decoquinate is a coccidiostat.
M2531 Clopidol Clopidol is an antiprotozoal agent.




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