Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M8245 | SPV-106 | SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. |
M8243 | CCT036477 | CCT036477 is an inhibitor of Wnt signaling. |
M8241 | MRT-10 | MRT-10 is a novel, high-affinity antagonist of smoothened (Smo). |
M8240 | 2002-H20 | 2002-H20 is an Alheimer′s Aβ peptide binder. |
M8238 | BV02 | BV02 is an inhibitor of the 14-3-3 scaffolding proteins docking site. |
M8237 | GPV574 | GPV574 is a derivative of the Class 1C antiarrhythmic compound propafenone. |
M8236 | Nomegestrol acetate | Nomegestrol acetate (NOMAc) is a potent, highly selective progestogen, a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors. |
M8235 | ABT-751 hydrochloride | ABT-751 is an orally bioavailable vascular disrupting agaent (VDA) with a broad spectrum of antitumor activity. |
M8234 | Loxiglumide | Loxiglumide is a small-molecule antagonist of the cholecystokinin receptor CCKA. |
M8233 | M30 dihydrochloride | M30 is a site-activated iron chelator and monoamine oxidase (MAO) inhibitor; with neuroprotective and anti-apoptotic activity. |
M8232 | BTZO-1 | BTZO-1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. |
M8230 | 2002-G12 | 2002-G12 binds Aβ peptide and was shown to inhibit Aβ42-induced killing of PC12 cells. |
M8229 | Conessine | Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors (Ki = 5. |
M8227 | L-Dopa ethyl ester | Levodopa ethyl ester is a precursor compound of levodopa, which has a high gastric solubility. |
M8226 | MEGX | Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine. |
M8225 | DiMNF | DiMNF is a naphthoflavone derivative, selective aryl hydrocarbon receptor modulator (SAhRM). |
M8224 | 1-Naphthohydroxamic Acid | 1-Naphthohydroxamic Acid is a cell-permeable, potent, and selective histone deacetylase 8 (HDAC8) inhibitor. |
M8220 | NSC 33994 | NSC 33994 is a potent and specific Jak2 inhibitor that inhibits a notorious mutation, Jak2-V617F, found in large number of myeloproliferative neoplasms. |
M8219 | CTP Inhibitor | CTP Inhibitor is an inhibitor of mitochondrial citrate transport protein, was the first purely competitive inhibitor to be discovered and is more potent than BTC. |
M8218 | NB001 | NB001, originally believed to be a selective inhibitor of adenylyl cyclase 1 (AC1), new evidence suggests NB001 does not interact with AC1 directly. |
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