Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-hydroxy-2-decenoic acid (10-H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
M8225 | DiMNF | DiMNF is a naphthoflavone derivative, selective aryl hydrocarbon receptor modulator (SAhRM). |
M8224 | 1-Naphthohydroxamic Acid | 1-Naphthohydroxamic Acid is a cell-permeable, potent, and selective histone deacetylase 8 (HDAC8) inhibitor. |
M8220 | NSC 33994 | NSC 33994 is a potent and specific Jak2 inhibitor that inhibits a notorious mutation, Jak2-V617F, found in large number of myeloproliferative neoplasms. |
M8219 | CTP Inhibitor | CTP Inhibitor is an inhibitor of mitochondrial citrate transport protein, was the first purely competitive inhibitor to be discovered and is more potent than BTC. |
M8218 | NB001 | NB001, originally believed to be a selective inhibitor of adenylyl cyclase 1 (AC1), new evidence suggests NB001 does not interact with AC1 directly. |
M8215 | CP-101,606 | Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. |
M8214 | CGP 37849 | CGP 37849 induces phencyclidine-like behavioral syndrome in amygdala-kindled rats that includes ataxia, locomotion and stereotypies. |
M8212 | MoTP | MoTP (also known as 33N14) reversibly blocks the specification of neural crest cells into melanocytes in zebrafish studies. |
M8210 | FR-171113 | FR171113 was the first non-peptide antagonist of the Protease Activated Receptor-1 (PAR1), also termed thrombin receptor. |
M8209 | Butyrylhydroxamic acid | Butyryl hydroxamic acid is a cell permeable HDAC inhibitor. |
M8208 | 4-Phenylbutyryl hydroxamic acid | 4-Phenylbutyryl hydroxamic acid is a cell permeable HDAC inhibitor which is about 100 times more potent than parent carboxylic acid among nine HDAC enzymes. |
M8207 | IMB-10 | IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. |
M8206 | PDI inhibitor 16F16 | 16F16 is a protein disulfide isomerase (PDI) inhibitor, first identified in a screen for compounds that prevent apoptosis induced by mutant huntingtin protein. |
M8205 | SR 142948A | SR 142948A is a non-peptide Neurotensin receptor antagonist. |
M8204 | VAHA | Hydroxamic acid derivatives of valproic acid exhibit anticonvulsant activity with no teratogenic activity in mouse neural tube defect model. |
M8202 | Sandoz 58-035 | Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. |
M8200 | SB 220025 trihydrochloride | SB 220025 is a potent, specific inhibitor of human p38 mitogen-activated protein (MAP) kinase, with an IC50 value of 60 nM and 50- to 1000-fold selectivity. |
M8198 | Sulprostone | Selective EP3 prostanoid receptor agonist. |
M8194 | SKI 5C | SKI 5C is a selective Sphingosine Kinase 1 (SPHK1) inhibitor. |
M8192 | SJ000025081 | SJ000025081 is a dihydropyridine effective against Plasmodium yoelii. |
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