| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M29854 | Dodecylphosphocholine | Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins. |
| M29848 | DM-Nitrophen tertasodium | DM-Nitrophen tertasodium is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light. DM-Nitrophen tertasodium can be used for study of Ca2+ signaling. |
| M29842 | MA-2029 | MA-2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4.9 nM). MA-2029 is selective for the motilin receptor over various other receptors and ion channels. MA-2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility. |
| M29833 | Ioxitalamic acid | Ioxitalamic acid is a water-soluble, nephrophilic, highly permeable X-ray iodinated contrast media. |
| M29832 | Managlinat dialanetil | Managlinat dialanetil (MB06322) is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase) for the treatment of type 2 diabetes[1] . |
| M29814 | NRX-1933 | NRX-1933 is a β-catenin:β-TrCP interaction enhancer for the development of small molecule degraders. |
| M29805 | TP-040 | TP-040 (O-GlcNAcase-IN-1) is a potent and novel OGA inhibitor with an IC50 value of 46 nM. |
| M29797 | CASK-IN-1 | CASK-IN-1 is a highly potent and selective CASK inhibitor with a Kd value of 0.022 μM. |
| M29782 | Dibutepinephrine | Dibutepinephrine is a sympathomimetic molecular. |
| M29781 | 5-C-heptyl-DNJ | 5-heptyl-DNJ is a potent GAA agonist with a Ki of 0.0047 μM. 5-C-heptyl-DNJ increases GAA activities by chaperrone effects. |
| M29776 | CHD1Li 6.11 | CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 µM for cat-CHD1L recombinant protein). CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties. |
| M29775 | 1-Monoelaidin | Monoelaidin is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| M29761 | Clofibride | Clofibride is an orally active hypolipaemic agent of pchlorophenoxyisobutyric type. Clofibride has weak toxicity and marked hypocholesterolaemic and hypotriglyceridaemic activity. Clofibride is converted into 4-chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) in vivo. |
| M29745 | GR148672X | GR148672X is a triacyglycerol hydrolase (TGH) inhibitor with an IC50 of 4 nM. |
| M29726 | TM-25659 | TM-25659 is a transcriptional co-activator with PDZ-binding motif (TAZ) modulator. Anti-osteoporotic and anti-obesity activities. |
| M29717 | XT2 | XT2 is a potent, orally active, and selective inhibitor of NF-κB-inducing kinase (NIK) with an IC50 of 9.1 nM. XT2 suppresses CCl4-induced upregulation of ALT, a key biomarker of acute liver injury. XT2 also decreases immune cell infiltration into the injured liver tissue. XT2 has the potential for the research of liver inflammatory diseases. |
| M29714 | Posovolone | Posovolone (Co 134444) is an orally active, neuroactive steroid. Posovolone has anticonvulsant and anxiolytic-like activity as well as ataxic effects. |
| M29712 | TH1760 | TH1760 is an inhibitor of NUDIX-type 15 (NUDT15) with an IC50 value of 25 nM. TH1760 sensitizes cells to 6-thioguanine by enhancing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 enhances the anti-leukemia effect of thiopurine. |
| M29702 | Mesembrenol | Mesembrenol (Chemotype c) is an alkaloid widely found in plants. Mesembrenol has potential application in quality control of raw materials and products of S.tortuosum. |
| M29683 | CYMAL-5 | CYMAL-5 is a cycloalkyl aliphatic saccharide. CYMAL-5 is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5 is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies. |
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