| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M31258 | 5-Chloro-2'-deoxyuridine | 5-Chloro-2'-deoxyuridine, a thymine analog, is to study the potential of hypochlorous acid damage to DNA and DNA precursors. |
| M31254 | Diethyl pyrocarbonate | Diethyl pyrocarbonate is a potent, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues. |
| M31155 | Progoitrin | Progoitrin (2-hydroxy-3-butenyl glucosinolate, PRO) is a naturally occurring thioglucoside with anti-thyroidal activity. |
| M31153 | Methyl linolenate | Methyl linolenate is a fatty acid methyl ester derived from α-linolenic acid, which is also an insect attractant. In addition, Methyl linolenate can inhibit the oxidation of unsaturated fatty acid methyl esters with an IC50 of 60 μM. |
| M31152 | Sodium L-lactate-13C3 solution | Sodium L-lactate-13C3 solution is a 13C-labeled L-lactate that can be used in studies related to lactate metabolism. |
| M31149 | Polygonatum sibiricum polysaccharides (70%) | Polygonatum sibiricum polysaccharides is a natural extract of Cyperus rotundus that exerts anticancer effects through the TLR4-MAPK/NF-κB signaling pathway and has antioxidant, anti-inflammatory, antibacterial, and neuroprotective activities, which can be used in studies related to Parkinson's disease (PD) and atherosclerosis (AS). |
| M31147 | Polygonatum sibiricum polysaccharides | Polygonatum sibiricum polysaccharides is a natural extract of Cyperus rotundus that exerts anticancer effects through the TLR4-MAPK/NF-κB signaling pathway and has antioxidant, anti-inflammatory, antibacterial, and neuroprotective activities, which can be used in studies related to Parkinson's disease (PD) and atherosclerosis (AS). |
| M31129 | Heptyl Butyrate | Heptyl butyrate is a flavor ester that occurs naturally in babaco fruit. It is an attractant for Vespula pensylvanica, a species of Yellow Jacket. Heptyl butyrate can be used as a flavoring ingredient in numerous consumer foods and beverages because of its fruity flavor. |
| M31114 | L-Homocysteine thiolactone hydrochloride | L-Homocysteine thiolactone hydrochloride is an amine reactive agent, is used to study post-translational modification of proteins, especially at lysine residues. |
| M31103 | Sodium L-lactate | Sodium L-lactate can be used as a casein toughening agent and water absorbent. sodium L-lactate can inhibit the multiplication of most spoilage bacteria and has different degrees of inhibition on many pathogenic bacteria such as Listeria monocytogenes, Salmonella and Clostridium botulinum. Sodium L-lactate is also used as an antioxidant synergist, emulsifier and humectant. |
| M31010 | TAT-Gap19 TFA | TAT-Gap19 TFA, a Cx mimetic peptide, is a specific connexin43 hemichannel (Cx43 HC) inhibitor. TAT-Gap19 TFA does not inhibits the corresponding Cx43 GJCs. TAT-Gap19 TFA traverses the blood-brain barrier and alleviate liver fibrosis in mice. |
| M30928 | ADAMTS-5 Inhibitor | ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 µM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1). |
| M30694 | RSM-932A | RSM-932A (TCD-717) is a specific ChoKα inhibitor with IC50s of 1 and 33 μM for human recombinant ChoKα and ChoKβ enzymes, respectively. RSM-932A acts as the “first in humans” compound targeting ChoKα. RSM-932A is potent in vitro anti-proliferative and in vivo anti-tumoral activity against human xenografts in mice, showing high efficacy with low toxicity profiles. |
| M30575 | Migalastat hydrochloride | Migalastat hydrochloride (DGJ; 1-Deoxygalactonojirimycin; GR181413A) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A. |
| M30498 | 5-Ethynyluridine | 5-Ethynyluridine (5-EU) is a potent cell-permeable nucleoside can be used to label newly synthesized RNA. 5-Ethynyluridine can be used for isolation and sequencing of nascent RNA from neuronal populations in vivo. 5-Ethynyluridine can be used to identify changes in transcription in vivo in nervous system disease models. |
| M30473 | SGA360 | SGA360 suppress inflammatory SAA1 signaling in an AHR-dependent manner through a mechanism that does not require AHR binding to its cognate response element (partial antagonist). |
| M30228 | MTOB sodium | MTOB sodium is a potent C-terminal binding protein (CtBP) inhibitor. MTOB sodium attenuates repetitive head injury-elicited neurologic dysfunction and neuroinflammation via inhibition of the transactivation activity of CtBP1 and CtBP2. MTOB sodium antagonizes the transcriptional regulatory activity of CtBP1 and CtBP2 by eviction from their target promoters in breast cancer cell lines. |
| M30209 | Coelenterazine h | Coelenterazine h is a derivative of Coelenterazine. Coelenterazine h is more sensitive to Ca2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca2+ concentrations. |
| M30183 | Chlorantraniliprole | Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM). |
| M30027 | Phosphatidylinositols, soya, sodium salts | Phosphatidylinositols, soya, sodium salts is a mixture of phosphatidylinositols. Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids between the different compartments of eukaryotic cells. They act by recruiting and/or activating effector proteins and thus are involved in regulating various cellular functions, such as vesicular budding, membrane fusion and cytoskeleton dynamics. |
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