| Cat.No. | Name | Information |
|---|---|---|
| M1970 | Paclitaxel | Paclitaxel is a diterpenoid derived from the bark of the plant Picea abies, and is also a microtubule polymer stabilizer, which promotes polymerization of microtubule proteins to inhibit depolymerization, maintains the stability of microtubule proteins, and inhibits cellular mitosis, and acts on human endothelial cells with an IC50 of 0.1 pM. |
| M3912 | Vinblastine sulfate | Vinblastine sulfate is an anti-mitotic agent which arrests the cell cycle in the G2/M-phase. |
| M1940 | Docetaxel | Docetaxel (Taxotere), a semi-synthetic analog of paclitaxel (Taxol), is a promoter of microtubule polymerization leading to cell cycle arrest at G2/M, apoptosis and cytotoxicity. |
| M55999 | 20-O-Demethyl-AP3 | 20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. |
| M55998 | Lisavanbulin dihydrochloride | Lisavanbulin (BAL-101553) dihydrochloride is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862). |
| M53349 | P34cdc2 Kinase Fragment | P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. |
| M53348 | Cemadotin | Cemadotin (LU103793) is an analogue of Dolastatin 15 which is naturally occurring cytotoxic peptides. |
| M50218 | VLS-1488 | VLS-1488 is an orally active KIF18A inhibitor that inhibits KIF18A microtubule-dependent ATPase activity with an IC50 value of 0.016 μM. |
| M49546 | ENMD-1198 | ENMD-1198 (IRC-110160), an orally active microtubule destabilizing agent, is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity. |
| M49523 | Tubulin/JAK2-IN-1 | Tubulin/JAK2-IN-1 is a dual inhibitor of Janus kinase 2 (JAK2) and microtubule. |
| M49522 | S-72 | S-72 inhibits tubulin polymerization and further triggers mitosis-phase cell cycle arrest and cell apoptosis, in addition to suppressing STAT3 signaling. |
| M44985 | Podophyllotoxinone | Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization. |
| M44837 | Deoxypodophyllotoxin | Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. |
| M41544 | ER degrader 7 | ER degrader 7 is an ERα and ERβ degrader. |
| M41543 | Tubulin inhibitor 34 | Tubulin inhibitor 34 is a potent anticancer agent. |
| M41542 | EAPB 02303 | EAPB 02303 is a microtubule-disrupting agent and inhibitor. |
| M41541 | KGP591 | KGP591 is a tubulin polymerization inhibitor (IC50 0.57 µM). |
| M41540 | Tubulozole | Tubulozole is an orally active synthetic microtubule inhibitor. |
| M41539 | Tubulin polymerization-IN-48 | Tubulin polymerization-IN-48 is a tubulin polymerization inhibitor. |
| M41538 | Tubulin polymerization-IN-43 | Tubulin polymerization-IN-43 is a tubulin polymerization inhibitor. |
| M41537 | Tubulin polymerization-IN-49 | Tubulin polymerization-IN-49 is a potent tubulin polymerization inhibitor. |
| M41536 | Epothilone F | Epothilone F is a Microtubule/Tubulin-stabilizing agent with anti-tumor activity. |
| M41535 | Tubulin polymerization-IN-12 | Tubulin polymerization-IN-12 is a tubulin polymerization inhibitor (IC50=0.75 μM). |
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