| Cat.No. | Name | Information |
|---|---|---|
| M1970 | Paclitaxel | Paclitaxel is a diterpenoid derived from the bark of the plant Picea abies, and is also a microtubule polymer stabilizer, which promotes polymerization of microtubule proteins to inhibit depolymerization, maintains the stability of microtubule proteins, and inhibits cellular mitosis, and acts on human endothelial cells with an IC50 of 0.1 pM. |
| M3912 | Vinblastine sulfate | Vinblastine sulfate is an anti-mitotic agent which arrests the cell cycle in the G2/M-phase. |
| M1940 | Docetaxel | Docetaxel (Taxotere), a semi-synthetic analog of paclitaxel (Taxol), is a promoter of microtubule polymerization leading to cell cycle arrest at G2/M, apoptosis and cytotoxicity. |
| M41534 | Synstab A | Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. |
| M41533 | MY-943 | MY-943 is a potent tubulin polymerization and LSD1 inhibitor with anticancer activity. |
| M41532 | Tubulin polymerization-IN-47 | Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor. |
| M41531 | MY-673 | MY-673 is a colchicine binding site inhibitor (CBSI), that inhibits tubulin polymerization. |
| M41530 | Tubulin inhibitor 38 | Tubulin inhibitor 38 is a tetrazole-based Tubulin inhibitor with antiproliferative potencies. |
| M41529 | Tubulin polymerization-IN-45 | Tubulin polymerization-IN-45, a tubulin-targeting agent, is a tubulin polymerization inhibitor. |
| M41528 | Tubulin polymerization-IN-44 | Tubulinpolymer-in-44 is a strong and effective Tubulin inhibitor, with an IC50 value of 0.21 μM. |
| M41527 | Tubulin polymerization-IN-11 | Tubulin polymerization-IN-11 is a potent tubulin polymerization inhibitor with an IC50 value of 3.4 µM. |
| M41526 | Tubulin inhibitor 37 | Tubulin inhibitor 37 is a Tubulin inhibitor that can effectively inhibit Tubulin aggregation (IC50=1.3 µM). |
| M41525 | Tubulin inhibitor 35 | Tubulin inhibitor 35 is a dual inhibitor of topoisomerase I (IC50=~50 μM) and tubulin polymerization (IC50=5.69 μM). |
| M41524 | Tubulin/HDAC-IN-2 | Tubulin/HDAC-IN-2 is a dual inhibitor of Tubulin and HDAC, with an IC50 of 0.403 μM, 0.591μM, 3.552μM, 0.459μM for HDAC1/2/3/6. |
| M41523 | PM050489 | PM050489 is an effective polyketone inhibitor of Microtubule/Tubulin that can be isolated from Madagascan sponge Lithoplocamia lithistoides. |
| M41522 | Tubulin inhibitor 33 | Tubulin inhibitor 33, a tubulin polymerization inhibitor, inhibits tubulin polymerization in a dose-dependent manner with an IC50 of 9.05 μM. |
| M41521 | Tubulin polymerization-IN-42 | Tubulin polymerization-IN-42, an indole-substituted furanone, is an inhibitor of tubulin polymerization with anti-cancer activity. |
| M41520 | Tubulin inhibitor 36 | Tubulin inhibitor 36 is a novel and potent tubulin inhibitor and inhibits the polymerization of microtubular protein then induces apoptosis with an IC50 value of 1.5±0.1 μM. |
| M40539 | Dolastatin 15 | Dolastatin 15, a heptasubunit condensed peptide derived from Dolabella auricularia, is also a potent antimitotic agent and microtubule destabilizer that inhibits mitosis by blocking microtubule assembly. In addition, Dolastatin 15 induces cell cycle arrest and apoptosis in multiple myeloma cells. It can also be used as an ADC cytotoxin for ADC development studies. |
| M38935 | Oryzalin | Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle. |
| M38934 | Glochidiol | Glochidiol is an orally active tubulin polymerization inhibitor with an IC50 of 2.76 μM. Glochidiol shows anti-cancer activity. |
| M38933 | Taxinine B | Taxinine B is a taxoid that can be isolated from Japanese Yew Taxus Cuspid. Taxinine B inhibits CaCl2-induced depolymerization of microtubule. Taxinine B is useful for overcoming multidrug resistance in tumor cells. |
| M38932 | 7-xylosyltaxol | 7-xylosyltaxol(Taxol-7-xyloside) is a taxol (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules. |
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