| Cat.No. | Name | Information |
|---|---|---|
| M49831 | Melanotan I | Melanotan I is a synthetic analog of α-Melanocyte Stimulating Hormone (α-MSH) and a potent non-selective melanocortin receptor (MCR) agonist that stimulates melanogenesis Melanotan I can be used in studies related to sunlight-induced skin cancer. |
| M49451 | MSG606 TFA | MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM) and a partial agonist at human MC3 and MC5 receptors (EC50 values of 59 and 1300 nM, respectively). In addition, MSG606 TFA reversed the hyperalgesia induced in female mice but had no effect in male mice. |
| M44663 | (-)-Isodocarpin | (-)-Isodocarpin (Isodocarpin), a diterpenoid, is a potent melanogenesis inhibitor with an IC50 of 0.19 μM in B16 4A5 cells. |
| M28807 | SHU 9119 acetate | SHU 9119 acetate is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively. |
| M13365 | Nonapeptide-1 acetate salt | Nonapeptide-1 acetate salt is apeptide hormone, which is a potent antagonist of α -melanocyte-stimulating hormone (α-MSH) with an IC50 value of 11 nM. Nonapeptide-1 (Melanostatine-5) acetate salt is a selective antagonist of MC1R (Ki=40 nM). |
| M11364 | α-MSH TFA | As an endogenous neuropeptide, alpha-melanocyte-stimulating hormone (TFA) is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic effects. α-MSH TFA is a posttranslational derivative of preopelanocorticoid (POMC). |
| M10677 | β-Melanocyte Stimulating Hormone TFA, human | β-Melanocyte Stimulating Hormone TFA, human is a 22-residue peptide, which acts as an endogenous melanocortin-4 receptor (MC4-R) agonist. |
| M10515 | JNJ-10229570 | JNJ-10229570 (UNII-N9IX402L35) is is a novel MC1R and MC5R antagonist, which inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R with IC50 values of 270 nM and 200 nM, respectively. |
| M10063 | Bremelanotide Acetate | Bremelanotide Acetate (PT-141 Acetate) is a peptide containing seven amino acids and is also a macrocyclic compound. In addition, Bremelanotide Acetate is an agonist of the melanocortin 4 receptor (MC4R). |
| M9908 | Setmelanotide | Setmelanotide is a selective agonist of the MC4 receptor, with EC50 values of 0.27 nM and 0.28 nM for human and rat MC4R, respectively. |
| M9822 | Melanotan-1 acetate | Melanotan-1 acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH). *This compound is unstable in solutions, freshly prepared is recommended. |
| M9572 | α-Melanocyte stimulating hormone | α-Melanocyte-stimulating hormone (α-MSH) is a tridecapeptide, mostly produced by the cells in the brain, pituitary and circulation. |
| M54224 | Adrenocorticotropic Hormone (ACTH) (4-10), human | Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist. |
| M54208 | γ1-MSH | γ1-MSH is a melanocortin MC3 receptor agonist, with a Ki of 34 nM for the rat MC3 receptor. |
| M54195 | γ-1-Melanocyte Stimulating Hormone (MSH), amide | γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. |
| M54104 | JKC363 | JKC363, a selective melanocortin MC4 receptor antagonist, has a 90-fold higher affinity at the MC4 receptor (IC50=0.5 nM) than at the MC3 receptor (44.9 nM). |
| M54062 | ACTH (11-24) | ACTH (11-24) is an adrenocorticotropic hormone (ACTH) receptor antagonist. |
| M53869 | [D-Trp8]-γ-MSH | [D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. |
| M53868 | SHU 9119 | SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively. |
| M53094 | ACTH (1-17) | ACTH (1-17), an adrenocorticotropin analogue, is a potent human melanocortin 1 (MC1) receptor agonist with a Ki of 0.21 nM. |
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