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β-Melanocyte Stimulating Hormone TFA, human is a 22-residue peptide, which acts as an endogenous melanocortin-4 receptor (MC4-R) agonist. β-Melanocyte Stimulating Hormone, human (β-MSH) has high affinity at both human MC4-R transfected into CHO cells (Ki=11.4±0.4 nM) and MC4-R in rat hypothalamic homogenates (Ki=5.0±0.4 nM).
| Molecular Weight | 2774.94 |
| Formula | C120H175F3N34O37S |
| CAS Number | 17908-57-5 ( free case) |
| Solubility (25°C) | Water ≥ 90 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
[3] P C Datta, et al. Neurosci Biobehav Rev. Alpha-melanocyte-stimulating hormone and behavior
[4] G A Bloomfield, et al. Proc R Soc Med. Beta-melanocyte stimulating hormone
[5] No authors listed. Br Med J. Melanocyte-stimulating hormone
| Related Melanocortin Receptor Products |
|---|
| CRN04894
CRN04894 is an orally active MC2R antagonist that demonstrates in vivo efficacy in rat model of adrenocorticotropic hormone (ACTH)-stimulated corticosterone secretion. |
| BMS-470539
BMS-470539 is a synthetic MC-1R agonist with potent anti-inflammatory properties. |
| PF-00446687
PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 ± 1 nM. |
| BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective melanocortin-1 receptor (MC-1R) agonist with an IC50 of 120 nM, an EC50 of 28 nM. |
| Undecylenoyl phenylalanine
Undecylenoyl phenylalanine is an antagonist for α-melanocyte-stimulating hormone (MSH) and β-adrenergic receptor (β-ADR) to reduce the melanogenesis in melanocytes. |
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Products are for research use only. Not for human use. We do not sell to patients.
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