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PF-00446687 

Cat. No. M56260

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PF-00446687  Structure

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Quality Control & Documentation
Biological Activity

PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 ± 1 nM.

Chemical Information
Molecular Weight 470.59
Formula C28H36F2N2O2
CAS Number 862281-92-3
Form Solid
Solubility (25°C) DMSO 55 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related Melanocortin Receptor Products
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CRN04894 is an orally active MC2R antagonist that demonstrates in vivo efficacy in rat model of adrenocorticotropic hormone (ACTH)-stimulated corticosterone secretion.

BMS-470539 

BMS-470539 is a synthetic MC-1R agonist with potent anti-inflammatory properties.

BMS-470539 dihydrochloride 

BMS-470539 dihydrochloride is a highly potent and selective melanocortin-1 receptor (MC-1R) agonist with an IC50 of 120 nM, an EC50 of 28 nM.

Undecylenoyl phenylalanine 

Undecylenoyl phenylalanine is an antagonist for α-melanocyte-stimulating hormone (MSH) and β-adrenergic receptor (β-ADR) to reduce the melanogenesis in melanocytes.

Adrenocorticotropic Hormone (ACTH) (4-10), human

Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist.

  Catalog
Abmole Inhibitor Catalog




Keywords: PF-00446687  supplier, Melanocortin Receptor, inhibitors, activators

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