| Cat.No. | Name | Information |
|---|---|---|
| M7325 | Rimonabant Hydrochloride | Rimonabant hydrochloride is a cannabinoid receptor antagonist, which binds selectively to central cannabinoid receptors (CB1) with high affinity |
| M29091 | ZCZ011 | ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain. |
| M28462 | Leelamine | Leelamine is a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine also inhibits pyruvate dehydrogenase kinases (PDKs). Leelamine exhibits anti-tumor activity. |
| M28030 | AM-6538 | AM6538 is a long-acting, high affinity and pseudo-irreversible cannabinoid (CB) antagonist. AM6538 is a structural analog of rimonabant. AM6538 can be effectively used to evaluate the apparent efficacy of cannabinoid full and partial agonists. AM6538 may be useful in future studies that require temporary reductions in cannabinoid receptor availability. |
| M27713 | COR170 | COR170 (11u) is a selective CB2 inverse-agonist which is a 4-quinolone-3-carboxylic acid derivative with a Ki value of 3.8 nM for CB2 receptor. COR170 can be used for the research of inflammation and neuroprotection. |
| M24918 | Nimacimab | Nimacimab (RYI-018) is a negative-allosteric modulating monoclonal antibody targeting CB1 receptor. Nimacimab can be used for research of metabolic diseases. |
| M13918 | Synaptamide | Synaptamide (Dehydroepiandrosteron; DHEA) is an endogenous metabolite and structural analogue of Anandamide. |
| M11426 | AM404 | AM404 is an endocannabinoid reuptake inhibitor that can block anandamide transport with IC50 values in the low mole range. The isolated rat hepatic artery was constricted by norepinephrine and relaxed by AM404. PEC50 value was 7.4 (corresponding EC50 value was 0.04 µM). It has neuroprotective effects. |
| M10789 | AZD1940 | AZD1940 is an orally active, high-affinity CB1/CB2 receptor agonist for CB1R and CB2R pKi the values are 7.93 and 9.06, respectively, and can be used in studies that relieve pain. |
| M8674 | AM4113 | AM4113 is a Cannabinoid CB-1 neutral antagonist. |
| M8321 | PF-514273 | PF-514273 is a highly selective CB1 antagonist. |
| M7071 | O-2050 | O-2050 is a putative CB1 silent antagonist; displays mixed activity at CB receptors. |
| M6430 | AM 6545 | AM 6545 is a high affinity and selective CB 1 antagonist. |
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