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Synaptamide (Dehydroepiandrosteron; DHEA) is an endogenous metabolite and structural analogue of Anandamide. Synaptamide binds to both the cannabinoid-1 and 2 (CB1 and CB2) cannabinoid receptors and has anti-inflammatory properties. Synaptamide is the first small-molecule endogenous ligand of an adhesion G protein-coupled receptor (aGPCR) .
| Molecular Weight | 371.56 |
| CAS Number | 162758-94-3 |
| Solubility (25°C) | Ethanol 25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Shilpa Sonti, et al. Metabolic studies of synaptamide in an immortalized dopaminergic cell line
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