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AM251

Cat. No. M2379

All AbMole products are for research use only, cannot be used for human consumption.

AM251 Structure
Size Price Availability Quantity
5mg USD 50  USD50 In stock
10mg USD 85  USD85 In stock
50mg USD 290  USD290 In stock
100mg USD 480  USD480 In stock
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Quality Control & Documentation
Biological Activity

AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain.

Chemical Information
Molecular Weight 555.24
Formula C22H21Cl2IN4O
CAS Number 183232-66-8
Solubility (25°C) DMSO 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ins B Correia-S, et al. AM251, a cannabinoid receptor 1 antagonist, prevents human fibroblasts differentiation and collagen deposition induced by TGF-β - An in vitro study

[2] Inmaculada Ruz-Maldonado, et al. The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling

[3] Tomoyo Yoshinaga, et al. AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells

[4] Sara Carpi, et al. AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells

[5] Izabela Bialuk, et al. AM251, cannabinoids receptors ligand, improves recognition memory in rats

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Keywords: AM251 supplier, Cannabinoid, inhibitors, activators

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