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(+)-Gallocatechin

Cat. No. M10218
(+)-Gallocatechin Structure
Size Price Availability Quantity
5mg USD 60  USD60 In stock
10mg USD 100  USD100 In stock
25mg USD 200  USD200 In stock
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Quality Control & Documentation
Biological Activity

(+)-Gallocatechin is found notably in green tea, it has moderate affinity to the human cannabinoid receptor and acts as an antioxidant.

Chemical Information
Molecular Weight 306.27
Formula C15H14O7
CAS Number 970-73-0
Solubility (25°C) DMSO 55 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ting Xiao, et al. Inflammation. Both Baicalein and Gallocatechin Gallate Effectively Inhibit SARS-CoV-2 Replication by Targeting M pro and Sepsis in Mice

[2] Nagarjuna Reddy Vendidandala, et al. Life Sci. Gallocatechin‑silver nanoparticle impregnated cotton gauze patches enhance wound healing in diabetic rats by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways

[3] Do Hwi Park, et al. Molecules. Neuroprotective Effect of Gallocatechin Gallate on Glutamate-Induced Oxidative Stress in Hippocampal HT22 Cells

[4] Priyanga Selvakumar, et al. Nutrients. Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer

[5] Almuth Hammerbacher, et al. Phytochemistry. Gallocatechin biosynthesis via a flavonoid 3',5'-hydroxylase is a defense response in Norway spruce against infection by the bark beetle-associated sap-staining fungus Endoconidiophora polonica

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