| Cat.No. | Name | Information |
|---|---|---|
| M2106 | Azilsartan | Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM. Azilsartan induces ROS formation and apoptosis in HepG2 cells. Azilsartan shows neuroprotective and anticancer activity. |
| M10146 | TRV-120027 TFA | TRV-120027 (also known as TRV027) is an angiotensin II receptor type 1 (AT1R) antagonist and engages ß-arrestins while blocking G-protein signaling. |
| M3507 | Valsartan | Valsartan is an angiotensin II receptor antagonist with IC50 of ranging from 39.5 to 116 μM. |
| M5731 | LCZ696 | LCZ696, consisting of Valsartan and Sacubitril in a 1:1 molar ratio, is a first-in-class dual-action angiotensin receptor-neprilysin inhibitor (ARNi,angiotensin receptor-neprilysin inhibitor) for the study of hypertension and heart failure. |
| M9079 | Angiotensin-(1-7) | Angiotensin (1-7) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7), inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC50 of 0.65 μM. |
| M41781 | Allisartan isoproxil | Allisartan isoproxil (ALS-3) is an orally potent, selective, non-peptide inhibitor of Angiotensin II Type 1. |
| M31339 | Trebananib | Trebananib (AMG 386) is a first-in-class (first-in-class) peptide that inhibits the interaction of Ang1 and Ang2 with their receptor Tie2, as well as an inhibitor of the non-VEGF-dependent angiogenic pathway. |
| M30325 | Angiotensin II 5-valine | Angiotensin II 5-valine is an agonist of angiotensin receptor. |
| M29982 | Novokinin | Novokinin is a peptide agonist of the angiotensin AT2 receptor. |
| M29474 | Azilsartan mopivabil | Azilsartan mopivabil is the potent antagonist of angiotensin II receptor. |
| M28645 | Azilsartan mepixetil | Azilsartan mepixetil is the antagonist of angiotensin II receptor. Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A). |
| M28464 | SL910102 | SL910102 is a nonpeptide angiotensin AT1 receptor antagonist. |
| M28171 | Olodanrigan sodium | Olodanrigan (EMA401) sodium is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. Olodanrigan sodium is under development as a neuropathic pain therapeutic agent. Olodanrigan sodium analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. |
| M28087 | Novokinin TFA | Novokinin TFA is a peptide agonist of the angiotensin AT2 receptor. |
| M27753 | TD-0212 TFA | TD-0212 TFA is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP. |
| M27752 | TD-0212 | TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP. |
| M17969 | 1-Methyl-2-[ (6Z,9Z)-6,9-pentadecadiene]-4 (1H)-quinolone | 1-Methyl-2-[（6Z,9Z）-6,9-pentadecadiene]-4（1H）-quinolone |
| M13914 | ZD 7155(hydrochloride) | ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist. |
| M13912 | Fimasartan | Fimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. |
| M13903 | Angiotensin II (3-8), human TFA | Angiotensin II (3-8), human (TFA) is a less effective agonist at the angiotensin AT1 receptor. |
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