Cat.No. | Name | Information |
---|---|---|
M58397 | Sulfo-LC-SPDP sodium | Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M58138 | DBCO-Maleimide | DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. |
M54791 | DBCO-acid | DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester, and agent-linker conjugates DBCO-PEG-MMAE. |
M49828 | Propargyl-C1-NHS ester | Propargyl-C1-NHS ester is a non-degradable linker that can be used to synthesize antibody coupled active molecules (ADCs). In addition, Propargyl-C1-NHS ester is a click chemistry reagent. It contains an Alkyne moiety and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an Azide moiety. |
M45209 | Maleimido-mono-amide-DOTA | Maleimido-mono-amide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M41004 | MC-VC-PAB-NH2 TFA | MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M40544 | Mirvetuximab soravtansine | Mirvetuximab soravtansine is an antibody-drug concatenation (ADC) containing a folate receptor alpha (frα)-conjugated antibody, a cleavable junction, and the medenosine alkaloid DM4, a potent microtubulin-targeting agent, that can be used in studies related to platinum-resistant epithelial ovarian cancer (EOC). |
M40540 | Sacituzumab govitecan | Sacituzumab govitecan is an antibody-drug concatenation (ADC) containing a humanized anti-trophoblast cell surface antigen 2 (TROP-2) antibody as well as the topoisomerase I inhibitor SN-38。It delivers high concentrations of SN-38 to tumors and can be used in studies related to triple-negative breast cancer. |
M13455 | Fmoc-Phe-Lys(Boc)-PAB-PNP TFA | Fmoc-Phe-Lys(Boc)-PAB-PNP TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M13454 | DSP Crosslinker | DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs). |
M13453 | DBCO-NHS ester | DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M13342 | DSG Crosslinker | DSG Crosslinker is a cleavable ADC linker that can be used to synthesize antibody-conjugated drugs (ADCs). |
M10414 | Fmoc-3VVD-OH | Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M10413 | Boc-Val-Cit-PAB | Boc-Val-Cit-PAB is a cleavable ADC linker used in making antibody-drug conjugates (ADCs). |
M10412 | Val-cit-PAB-OH | Val-cit-PAB-OH is a cathepsin cleavable ADC peptide linker for making MC-Val-Cit-PAB, which is also known as MC-Val-Cit-PAB-OH. |
M10411 | Fmoc-Val-Cit-PAB-PNP | Fmoc-Val-Cit-PAB-PNP is a cleavable peptide ADC linker which used in the synthesis of antibody-drug conjugates (ADCs). |
M10410 | Fmoc-Val-Cit-PAB | Fmoc-Val-Cit-PAB-OH is a cleavable useful heterobifunational linker for making Antibody-Drug-Conjugates (ADC). |
M10409 | Mc-Val-Cit-PAB | Mc-Val-Cit-PAB is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). |
M10401 | SPDP Crosslinker | SPDP crosslinker, or SPDP NHS ester, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. *The compound is unstable in solutions, freshly prepared is recommended |
M10092 | Sulfo-NHS | Sulfo-NHS is a peptide condensing agent, can form a stable active ester intermediate, used to prepare hydrophilic active ester, for example as a protein cross-linking agent. N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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