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DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester, and agent-linker conjugates DBCO-PEG-MMAE. DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
| Molecular Weight | 305.33 |
| Formula | C19H15NO3 |
| CAS Number | 1353016-70-2 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | 4°C, sealed |
| Related ADC Linker Products |
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| Sulfo-LC-SPDP sodium
Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| DBCO-Maleimide
DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. |
| SPDB-sulfo
SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) . |
| Tr-PEG5-OH
Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| DBCO-amine
DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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