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ADC Linker Antibody-drug Conjugate Linker

Cat.No.  Name Information
M59051 8-Azido-3,6-dioxaoctanoic Acid Cyclohexylamine Salt 8-Azido-3,6-dioxaoctanoic Acid Cyclohexylamine Salt is a azido-modified PEG2 acid, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
M58963 DOTA-​NHS-ester DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors.
M58397 Sulfo-LC-SPDP sodium Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
M58138 DBCO-Maleimide DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
M54791 DBCO-acid DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester, and agent-linker conjugates DBCO-PEG-MMAE.
M49828 Propargyl-C1-NHS ester Propargyl-C1-NHS ester is a non-degradable linker that can be used to synthesize antibody coupled active molecules (ADCs). In addition, Propargyl-C1-NHS ester is a click chemistry reagent. It contains an Alkyne moiety and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an Azide moiety.
M45209 Maleimido-mono-amide-DOTA Maleimido-mono-amide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
M41004 MC-VC-PAB-NH2 TFA MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
M40546 Trastuzumab Emtansine Trastuzumab Emtansine is a HER2-targeting antibody-drug concatenation (ADC) that can be used in studies related to HER2-positive metastatic breast cancer.
M40544 Mirvetuximab soravtansine Mirvetuximab soravtansine is an antibody-drug concatenation (ADC) containing a folate receptor alpha (frα)-conjugated antibody, a cleavable junction, and the medenosine alkaloid DM4, a potent microtubulin-targeting agent, that can be used in studies related to platinum-resistant epithelial ovarian cancer (EOC).
M40540 Sacituzumab govitecan Sacituzumab govitecan is an antibody-drug concatenation (ADC) containing a humanized anti-trophoblast cell surface antigen 2 (TROP-2) antibody as well as the topoisomerase I inhibitor SN-38。It delivers high concentrations of SN-38 to tumors and can be used in studies related to triple-negative breast cancer.
M13455 Fmoc-Phe-Lys(Boc)-PAB-PNP TFA Fmoc-Phe-Lys(Boc)-PAB-PNP TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
M13454 DSP Crosslinker DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).
M13453 DBCO-NHS ester DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
M13342 DSG Crosslinker DSG Crosslinker is a cleavable ADC linker that can be used to synthesize antibody-conjugated drugs (ADCs).
M10414 Fmoc-3VVD-OH Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
M10413 Boc-Val-Cit-PAB Boc-Val-Cit-PAB is a cleavable ADC linker used in making antibody-drug conjugates (ADCs).
M10412 Val-cit-PAB-OH Val-cit-PAB-OH is a cathepsin cleavable ADC peptide linker for making MC-​Val-​Cit-​PAB, which is also known as MC-​Val-​Cit-​PAB-OH.
M10411 Fmoc-Val-Cit-PAB-PNP Fmoc-Val-Cit-PAB-PNP is a cleavable peptide ADC linker which used in the synthesis of antibody-drug conjugates (ADCs).
M10410 Fmoc-Val-Cit-PAB Fmoc-Val-Cit-PAB-OH is a cleavable useful heterobifunational linker for making Antibody-Drug-Conjugates (ADC).




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