Cat.No. | Name | Information |
---|---|---|
M41006 | SC209 intermediate-1 | SC209 intermediate-1 is an ADC linker. |
M41005 | Tup hydrochloride | Tup hydrochloride is a cleavable ADC linker. |
M41004 | MC-VC-PAB-NH2 TFA | MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M41003 | Mal-L-PA-NH-Boc | Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M41002 | AcLys-PABC-VC-Aur0101 intermediate-1 | AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. |
M40879 | [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid | [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid is a PEG-based degradable ADC linker and PROTAC linker that can be used in the synthesis of antibody active molecule couplers (ADCs) and PROTACs. |
M40546 | Trastuzumab Emtansine | Trastuzumab Emtansine is a HER2-targeting antibody-drug concatenation (ADC) that can be used in studies related to HER2-positive metastatic breast cancer. |
M40545 | Inotuzumab Ozogamicin | Inotuzumab Ozogamicin is an antibody-drug concatenation (ADC) containing an anti-CD22 monoclonal antibody as well as spinosad for studies related to acute lymphoblastic leukemia (ALL). |
M40544 | Mirvetuximab soravtansine | Mirvetuximab soravtansine is an antibody-drug concatenation (ADC) containing a folate receptor alpha (frα)-conjugated antibody, a cleavable junction, and the medenosine alkaloid DM4, a potent microtubulin-targeting agent, that can be used in studies related to platinum-resistant epithelial ovarian cancer (EOC). |
M40543 | Tisotumab Vedotin | Tisotumab Vedotin is a tissue factor-directed antibody-drug conjugate (ADC) containing a tissue factor-specific fully human monoclonal antibody (TF-011) conjugated to monomethylmethane auristatin E (MMAE), which can be used in studies related to cervical cancer. |
M40542 | Belantamab Mafodotin | Belantamab Mafodotin is a first-in-class antibody-drug concatenation (ADC) against B cell maturation antigen (BCMA). It contains antibodies targeting BCMA as well as the microtubule inhibitor monomethylauristatin F (MMAF) and may be used in studies related to multiple myeloma (MM). |
M40540 | Sacituzumab govitecan | Sacituzumab govitecan is an antibody-drug concatenation (ADC) containing a humanized anti-trophoblast cell surface antigen 2 (TROP-2) antibody as well as the topoisomerase I inhibitor SN-38。It delivers high concentrations of SN-38 to tumors and can be used in studies related to triple-negative breast cancer. |
M38624 | Boc-Hyp-OH | Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
M38623 | Eicosanedioic acid | Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis |
M38621 | H-Hyp-OMe hydrochloride | H-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
M30995 | DBCO-PEG4-acetic-Val-Cit-PAB | DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M30969 | Mal-amido-PEG2-NHS ester | Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. |
M25056 | Upifitamab rilsodotin | Upifitamab rilsodotin (XMT-1536) is an antibody-drug conjugate targeting NaPi2b. Upifitamab rilsodotin can be used for the research of cancer, including Ovarian cancer. |
M24699 | Vandortuzumab vedotin | Vandortuzumab vedotin (DSTP 3086S) is an antibody-drug-conjugate to target prostate cancer. |
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