| Cat.No. | Name | Information |
|---|---|---|
| M2147 | Ilomastat | Ilomastat (GM6001; Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor with Ki values of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM and 0.36 nM for MMPs -1, -2, -3, -7, -8, -9, -12, -14 and -26, respectively. Ilomastat (GM6001; Galardin) reduces infarct volume following middle cerebral artery occlusion in an ischemic mouse model. |
| M4907 | Doxycycline Hyclate | Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. |
| M7413 | TMI 1 | TMI 1 is a adam 17 (TACE) and MMP inhibitor; orally bioavailable. |
| M9373 | T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects. |
| M4779 | Cordycepin | Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. |
| M9466 | S-methyl-KE-298 | S-methyl-KE-298 is an active metabolite of KE-298. KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells. |
| M8732 | T-26c | T-26c is a highly potent, selective and cell-permeable matrix metalloproteinases 13 (MMP-13) inhibitor. |
| M8156 | SB-3CT | SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. |
| M8041 | CP-101537 | Cp-101537 is an MMP inhibitor, a candidate compound for the treatment of myocardial infarction, and an antibacterial compound. |
| M7736 | CL-82198 | CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. |
| M7454 | UK 356618 | UK 356618 is a potent and selective MMP-3 inhibitor. |
| M6749 | GI 254023X | GI 254023X is a selective ADAM10 metalloprotease inhibitor, with IC50 of 5.3 nM. |
| M6614 | CL 82198 hydrochloride | CL 82198 hydrochloride is a selective inhibitor of MMP-13. |
| M6216 | TAPI-2 | TAPI-2 is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20±10 μM for MMP. |
| M6215 | TAPI-0 | TAPI-0 is an inhibitor which blocks the maturation of cytokines, soluble cyokine receptors and other proteins that require the action of proteases. |
| M4612 | Arctigenin | Arctigenin ((-) -arctigenin) is a bioactive lignan that can be used as an antitumor agent. Arctigenin has effective antioxidant, anti-inflammatory and antiviral activities. Arctigenin can be used to study metabolic disorders and central nervous system dysfunction. |
| M4473 | Morroniside | Morroniside plays a neuroprotective role by inhibiting neuronal apoptosis and mMP9/2 expression. |
| M4463 | Abametapir | Abametapir (HA-44, BRN 0123183) is an inhibitor of metalloproteinases critical for louse survival and egg development. |
| M4314 | Lucidenic-acid-A | Lucideric acid A, A natural product isolated from Ganoderma lucidum, can inhibit THE activity of MMP-9 induced by PMA, and has an anti-invasion effect on liver cancer cells. |
| M4311 | Lucidenic-acid-C | Lucidenic acid C, a natural product isolated from Ganoderma lucidum, can inhibit THE activity of MMP-9 induced by PMA, and has an anti-invasion effect on liver cancer cells. |
| M4210 | EGC | EGC is a potent inhibitor of amyloidogenic cystatin I66Q amyloid fibril formation in vitro, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. |
| M4079 | (R)Ginsenoside-Rh2 | 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as an anti-proliferative agent in cells. It has anticancer effects by blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis and has anti-inflammatory and antioxidant activities. 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of mouse and human γ herpevirus 68 (MHV-68) with an IC50 of 2.77 μM against mouse MHV-68. |
| M2829 | Marimastat | Marimastat (BB-2516) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 with IC50 of 3 nM, 5 nM, 6 nM, 9 nM and 13 nM, respectively. |
| M2564 | NSC 405020 | NSC 405020 is a noncatalytic inhibitor of MT1-MMP, directly interacts with PEX domain of MT1-MMP, affects PEX homodimerization but not catalytic activity of MT1-MMP. |
| M2433 | Batimastat | Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
