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Isoginkgetin is a naturally occurring diflavone with antitumor activity. Isoginkgetin directly inhibits chymotrypsin-like, trypsin-like, and caspase - like activities of the 20S proteasome. Isoginkgetin is an inhibitor of MMP-9 and also an inhibitor of pre-mrna Splicing.
| Molecular Weight | 566.51 |
| Formula | C32H22O10 |
| CAS Number | 548-19-6 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 2-8°C, protect from light |
| Related MMP Products |
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| KP-457
KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with IC50 of 11.1 nM (cell-free assay). KP-457 also cleaves various molecules such as GPIbα, GPV, and TNF-α. |
| MMP2-IN-1
MMP2-IN-1 is a moderate potenet MMP2 inhibitor with IC50 of 6.8 µM. MMP2-IN-1 exhibits remarkable antiproliferative activity in certain cancer cells by arresting the cell cycle and inducing apoptosis. |
| MMP-9 Inhibitor I
MMP-9 inhibitor I is a cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). MMP-9 inhibitor I also inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 IC50 = 113 nM) at higher concentrations. |
| BPHA
BPHA is a potent and orally active MMP-2, MMP-9 and MMP-14 inhibitor with IC50s of 12 nM, 16 nM and 17 nM, respectively. |
| ONO-4817
ONO-4817 is a potent inhibitor of matrix metalloproteinase (MMP). |
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