| Cat.No. | Name | Information |
|---|---|---|
| M2147 | Ilomastat | Ilomastat (GM6001; Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor with Ki values of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM and 0.36 nM for MMPs -1, -2, -3, -7, -8, -9, -12, -14 and -26, respectively. Ilomastat (GM6001; Galardin) reduces infarct volume following middle cerebral artery occlusion in an ischemic mouse model. |
| M4907 | Doxycycline Hyclate | Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. |
| M7413 | TMI 1 | TMI 1 is a adam 17 (TACE) and MMP inhibitor; orally bioavailable. |
| M9373 | T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects. |
| M4779 | Cordycepin | Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. |
| M52561 | GPLGIAGQ | GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. |
| M52560 | FFAGLDD | FFAGLDD is MMP9 selective cleavage peptides, which used for cytosolic delivery of Doxorubi-cin (DOX) and achieve temporally and spatially controlled slow drug delivery and release. |
| M50179 | ARO-MMP7 | ARO-MMP7 is a small interfering RNA (siRNA) that reduces matrix metalloproteinase 7 (MMP7) expression and can be used in studies related to idiopathic pulmonary fibrosis (IPF). |
| M49482 | Otaplimastat | Otaplimastat is a matrix metalloproteinase (MMP) inhibitor that competitively blocks NMDA receptor-mediated excitotoxicity. In addition, Otaplimastat has antioxidant activity and may be used in studies related to cerebral ischemic injury. |
| M42522 | TNO211 | TNO211 is a biological active peptide. |
| M42521 | NFF-3 | NFF-3, the peptide, is a selective MMP substrate. |
| M42520 | FN-439 TFA | FN-439 TFA is a selective collagenase-1 inhibitor. |
| M42519 | NFF-3 TFA | NFF-3 TFA, the peptide, is a selective MMP substrate. |
| M42518 | MMP-7-IN-2 | MMP-7-IN-2 is a selective MMP7 inhibitor, with an IC50 of 16 nM. |
| M42517 | ND-322 hydrochloride | ND-322 hydrochloride is a potent and selective water-soluble gelatinase inhibitor. |
| M42516 | MMP-13-IN-1 | MMP-13-IN-1 is a potent and selective inhibitor of MMP-13 with a IC50 value of 16 nM. |
| M42515 | MMP-9-IN-6 | MMP-9-IN-6 is a MMP-9 inhibitor with IC50 value of 50 μM, which has good anti-ulcer effect. |
| M42514 | RXP470.1 | RXP470.1 (RXP-470) is a potent, selective MMP-12 inhibitor with a Ki of 0.2 nM against human MMP-12. |
| M42513 | VPLSLYSG | VPLSLYSG is an octapeptide that can be degraded by matrix metalloproteinase-9 (MMP-9), MMP-1 and MMP-2. |
| M42512 | MMP13-IN-4 | MMP13-IN-4 is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM), involved in osteoarthritis (OA). |
| M42511 | MMP13-IN-5 | MMP13-IN-5 is a potent and selective inhibitor of MMP-2/MMP-13 (IC50=3.6 μM/14.6 μM), involved in osteoarthritis (OA). |
| M42510 | MMP-8 inhibitor-1 | MMP-8 inhibitor-1, a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability. |
| M42509 | PF-00356231 | PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). |
| M39161 | Nudol | Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma. |
| M39160 | Xanthopurpurin | Xanthopurpurin, an anthraquinone glycoside, isolated from the roots of Rubia akane, shows mainly strong inhibition of collagen-induced platelet aggregation. |
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