Cat.No. | Name | Information |
---|---|---|
M2147 | Ilomastat | Ilomastat (GM6001; Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor with Ki values of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM and 0.36 nM for MMPs -1, -2, -3, -7, -8, -9, -12, -14 and -26, respectively. Ilomastat (GM6001; Galardin) reduces infarct volume following middle cerebral artery occlusion in an ischemic mouse model. |
M4907 | Doxycycline Hyclate | Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. |
M7413 | TMI 1 | TMI 1 is a adam 17 (TACE) and MMP inhibitor; orally bioavailable. |
M9373 | T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects. |
M4779 | Cordycepin | Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. |
M14469 | CTS-1027 | CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1. |
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