Natural Products

Cat.No.	Name	Information
M39228	FMoc-D-3-Thienylalanine	FMoc-D-3-Thienylalanine is an alanine derivative.
M39227	Fmoc-L-3-Cyanophenylalanine	Fmoc-L-3-Cyanophenylalanine is a phenylalanine derivative.
M39226	Fmoc-Asp-Oall	Fmoc-Asp-Oall is an aspartic acid derivative.
M39225	FMOC-D-4-Chlorophe	FMOC-D-4-Chlorophe is a phenylalanine derivative.
M39224	Fmoc-L-glutamic acid 5-tert-butyl ester	Fmoc-L-glutamic acid 5-tert-butyl ester is a glutamic acid derivative.
M39223	Fmoc-D-2-Trifluoromethylphenylalanine	Fmoc-D-2-Trifluoromethylphenylalanine is a phenylalanine derivative.
M39222	Echinulin	Echinulin (Echinuline) is a cyclic dipeptide carrying a triprenylated indole moiety. Echinulin contributes to the activation of T cell subsets, which leads to NF-κB activation.Echinulin exerts its immune roles by the NF-κB pathway.Echinulin has the potential to serve as a immunotherapeutic agent.
M39221	Sootepin D	Sootepin D (compound 6), a triterpene from the apical bud of Gardenia sootepensis, inhibits TNF-α-induced NF-κB activity with an IC50 of 8.3μM. Sootepin D has anti-inflammatory activity.
M39220	Dendrophenol	Dendrophenol (Moscatilin) acts as a NF-κB inhibitor. Antineoplastic activity.
M39219	Icariside F2	Icariside F2 is a potent NF-κB inhibitor with an IC50 value of 16.25 μM. Icariside F2 is an aromatic glycoside isolated from the leaves of E. ulmoides Oliver. Icariside F2 has anti-inflammatory activity.
M39217	Laurotetanine	Laurotetanine ((+)-Laurotetanine) is an potent and orally active isoquinoline alkaloid, it exerts an anti-asthmatic effect by inhibition of IgE, histamine, and inflammatory reactions via down-regulating MUC5AC and NF-κB signaling pathways.
M39216	Cudraflavone B	Cudraflavone B is a prenylated flavonoid with anti-inflammatory and anti-tumor properties. Cudraflavone B is also a dual inhibitor of COX-1 and COX-2. Cudraflavone B blocks the translocation of nuclear factor κB (NF-κB) from the cytoplasm to the nucleus in macrophages.
M39214	Coronalolic acid	Coronalolic acid, extract from the apical bud of Gardenia sootepenesis Hutch, inhibits TNF-α-induced NF-κB activity and NO production.
M39212	Stipuleanoside R2	Stipuleanoside R2 inhibits NF-κB activation stimulated by TNFα in a dose-dependent manner with IC50 value of 4.1 μM.
M39211	(Rac)-Myrislignan	(Rac)-Myrislignan is the racemate of Myrislignan. Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan attenuates LPS-induced inflammation reaction in murine macrophage cells through inhibition of NF-kB signalling pathway activation.
M39210	7,8-Didehydrocimigenol	7,8-Didehydrocimigenol inhibits TNF-α-induced VCAM-1 expression, inhibits NF-kB activity and phosphorylation of ERK1/2 and Akt, increases PPAR-γ expression. 7,8-Didehydrocimigenol can be used for the research of cardiovascular disorders such as atherosclerosis.
M39209	Toralactone	Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism.
M39207	4′-Hydroxywogonin	4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis.
M39206	Peucedanocoumarin III	Peucedanocoumarin III is an inhibitor of (alpha)-synuclein and Huntington protein aggregates that enhances the clearance of nuclear and cytoplasmic β23 aggregates and prevents cytotoxicity induced by disease-associated proteins.
M39205	Procyanidin B2 3,3'-di-O-gallate	Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway.

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