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4′-Hydroxywogonin

Cat. No. M39207

All AbMole products are for research use only, cannot be used for human consumption.

4′-Hydroxywogonin Structure

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Quality Control & Documentation
Biological Activity

4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis.

Chemical Information
Molecular Weight 300.26
Formula C16H12O6
CAS Number 57096-02-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tomasz Tronina et al. Int J Mol Sci. Simple and Rapid Method for Wogonin Preparation and Its Biotransformation

[2] Dongdong Sun et al. Chem Biol Interact. 4'-hydroxywogonin inhibits colorectal cancer angiogenesis by disrupting PI3K/AKT signaling

[3] Peng-Fei Li et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi. [Effect of 4' -Hydroxywogonin on Proliferation and Apoptosis of Human Acute Lymphoblastic Leukemia Cells]

[4] Chao Fan et al. PLoS One. 4'-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice

[5] Palatheeya Sujatha et al. Nat Prod Res. Flavonoids of Dikamali: A phytochemical reinvestigation

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Keywords: 4′-Hydroxywogonin supplier, IκB/IKK, inhibitors, activators

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