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  Catalog
Abmole Inhibitor Catalog 2017

ATM/ATR

Inhibitors

Cat.No.  Name Information
M5138 Mirin Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.
M3570 Candesartan Cilexetil Candesartan Cilexetil is a specific nonpeptide Ang II receptor (ATR) antagonist and the procompound of candesartan which is an ATR antagonist with an IC50 of 15 μg/kg.
M3115 VE-822 VE-822 is an ATR inhibitor with IC50 of 19 nM.
M2505 CGK 733 CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM.
M2412 AZ20 AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM, 8-fold selectivity over mTOR.
M2309 CP-466722 CP-466722 is an potent and reversible ATM inhibitor.
M2187 ETP-46464 ETP-46464 is a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα and ATM with IC50 of 0.6, 14, 36, 170 and 545 nM, respectively.
M2047 VE-821 VE-821 is a highly selective and potent ATR inhibitor with IC50 of 26 nM.
M1998 KU-60019 KU-60019 is a potent ATM kinase inhibitor with IC50 of 6.3 nM.
M1801 KU-55933 KU-55933 is a cell-permeable ATP-competitive inhibitor of ATM (IC50 = 13 nM; Ki = 2.2 nM) with selectivity over other PIKK family kinases (IC50 = 2.5, 9.3, 16.6 μM for DNAPK, mTOR, PI 3-K, respectively; IC50 > 100 μM for PI 4-K and ATR).


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