Free shipping on all orders over $ 500
  Catalog
Abmole Inhibitor Catalog 2017

ATM/ATR

Inhibitors

Cat.No.  Name Information
M6080 BAY-1895344 Identification of potent, highly selective and orally available ATR inhibitor BAY 1895344 with favorable PK properties and promising efficacy in monotherapy and combination in preclinical tumor models
M5138 Mirin Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.
M3570 Candesartan Cilexetil Candesartan Cilexetil is a specific nonpeptide Ang II receptor (ATR) antagonist and the procompound of candesartan which is an ATR antagonist with an IC50 of 15 μg/kg.
M3115 VE-822 VE-822 is an ATR inhibitor with IC50 of 19 nM.
M2505 CGK 733 CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM.
M2412 AZ20 AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM, 8-fold selectivity over mTOR.
M2309 CP-466722 CP-466722 is an potent and reversible ATM inhibitor.
M2187 ETP-46464 ETP-46464 is a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα and ATM with IC50 of 0.6, 14, 36, 170 and 545 nM, respectively.
M2047 VE-821 VE-821 is a highly selective and potent ATR inhibitor with IC50 of 26 nM.
M1998 KU-60019 KU-60019 is a potent ATM kinase inhibitor with IC50 of 6.3 nM.
M1801 KU-55933 KU-55933 is a cell-permeable ATP-competitive inhibitor of ATM (IC50 = 13 nM; Ki = 2.2 nM) with selectivity over other PIKK family kinases (IC50 = 2.5, 9.3, 16.6 μM for DNAPK, mTOR, PI 3-K, respectively; IC50 > 100 μM for PI 4-K and ATR).


Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.