c-Fms-IN-1 - Search Results | AbMole BioScience

About 7 results found for searched term "c-Fms-IN-1" (0.119 seconds)

Cat.No.	Name	Target
M22327	c-Fms-IN-1	Others
	c-Fms-IN-1
M43481	c-Fms-IN-14	CSF-1R (c-Fms)
	c-Fms-IN-14 is a c-Fms inhibitor with an IC50 value of 4 nM.
M4955	PLX647	CSF-1R (c-Fms)
	PLX-647
	PLX647 is a highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respectively.
M8758	GW806742X	Necroptosis
	GW806742X is an ATP site-targeing kinase inhibitor (IC50 in nM = 2/VEGFR2, 15/SRC, 47/C-FMS, 851/GSK3, 9016/ERBB2, 9120/FGFR) with potent antiproliferation activity against cancer cultures (IC50 in nM = 5/HUVEC-v, 424/HUVEC-b, 81/HEF, 453/MDA468, 470/A375P, 693/HT29, 734/PC3), GW806742X is now better known as Compound 1 for its anti-necroptosis activity via affinity interaction with ML
M9685	cFMS Receptor Inhibitor II	CSF-1R (c-Fms)
	cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor.
M28057	JTE-952	CSF-1R (c-Fms)
	JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis.
M43479	Sotuletinib hydrochloride	CSF-1R (c-Fms)
	Sotuletinib (BLZ945) hydrochloride is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM.