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JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis.
| Molecular Weight | 518.6 |
| Formula | C30H34N2O6 |
| CAS Number | 1255303-54-8 |
| Form | Solid |
| Storage | 4°C, protect from light, dry, sealed |
| Related CSF-1R (c-Fms) Products |
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