Certificate of Analysis

 

Product Name: JTE-952 
Catalog Number: M28057
CAS Number: 1255303-54-8

Physical and Chemical Properties
Formula: C30H34N2O6
Molecular Weight: 518.6
Form: Solid
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: JTE-952  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.