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Tinengotinib

Cat. No. M43943

All AbMole products are for research use only, cannot be used for human consumption.

Tinengotinib Structure
Synonym:

TT 00420

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Quality Control & Documentation
Biological Activity

Tinengotinib is a modulator of several protein kinases, such as Aurora kinase, VEGFR kinase, and CSF-1R, etc. Tinengotinib can be used in studies related to diseases mediated by abnormalities in these kinases.

Chemical Information
Molecular Weight 394.86
Formula C20H19ClN6O
CAS Number 2230490-29-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sarina A Piha-Paul, et al. Oncologist. First-In-Human Phase I Study of Tinengotinib (TT-00420), a Multiple Kinase Inhibitor, as a Single Agent in Patients With Advanced Solid Tumors

[2] Shumao Ni, et al. Eur J Pharm Sci. In vitro and in vivo pharmacokinetics, disposition, and drug-drug interaction potential of tinengotinib (TT-00420), a promising investigational drug for treatment of cholangiocarcinoma and other solid tumors

[3] Peng Peng, et al. Mol Cancer Ther. Tinengotinib (TT-00420), a Novel Spectrum-Selective Small-Molecule Kinase Inhibitor, Is Highly Active Against Triple-Negative Breast Cancer

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  Catalog
Abmole Inhibitor Catalog




Keywords: Tinengotinib, TT 00420 supplier, CSF-1R (c-Fms), inhibitors, activators

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